Cancer is a big problem in the history of human medicine, and there is no way to completely cure it at present. In the face of cancer with extremely high mortality, life is fragile. No matter whether it is poor or rich, famous or unknown, we often see the news that celebrities have died of cancer, and we can’t help sighing, but there are also some wonderful experiences of anti-cancer success!　 Many cancer patients often lose confidence in life after learning that they have cancer, do not actively treat them, or even resist treatment, and feel that treatment is unnecessary, and treatment is a waste of money. In fact, this idea is not correct. Don’t give up until the last moment. Even if cancer has not been completely overcome, after scientific and reasonable treatment with many patients, life can be continued, and even clinical cure or long-term survival with tumors can be achieved! Nowadays, there are many treatments for cancer. If it is found as early as possible and treated actively, one third of cancer can be cured. Medical "cure" is different from what people usually understand. The clinical cure here refers to the disappearance of symptoms and signs after treatment, and the tumor can not be found after image review for more than 5 years.

Today, Xiaobian, a cancer-free home, will share the stories of four celebrities who have succeeded in fighting cancer, and see how they fight cancer. I hope to give some reference and motivation to all cancer friends!

Kai-Fu Lee: From the late stage of cancer to the disappearance of tumor, chemotherapy+targeted therapy against advanced lymphoma.

　 On September 5th, 2013, 52-year-old Kai-fu Lee, the founder of Innovation Factory, announced that he had stage IV follicular lymphoma and had to leave work for treatment. In February 2015, he announced the results of his physical examination, indicating that the tumor in the body is not obvious at present. In June of the same year, Kai-fu Lee said that he had not found any lesions in his last two examinations and ridiculed himself as "Li Kangfu". It took Kai-fu Lee less than two years from finding out the cancer until the focus was completely gone. His anti-cancer experience is worth learning from. 　

Lymphoma, also known as lymphoma, occurs in the lymphatic system and is one of the malignant diseases of the blood system. In fact, we are no strangers. Besides Kai-Fu Lee, celebrities such as Luo Jing, Asan and Cindy Lee have also suffered from lymphoma. The incidence of lymphoma is actually not too high in malignant tumors, which is about 5/100,000. It can occur at any age, but it is mainly in middle-aged people aged 30-50. The malignant degree of different types of lymphoma varies greatly, which can be roughly divided into: inertia, aggression and high aggression. Inertial lymphoma is similar to chronic diseases, while high aggression is like a "death warrant"! There are many types of lymphoma, but as long as we know, lymphoma can be divided into Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL), the latter accounting for about 90%, and diffuse large B-cell lymphoma is the main type (40%~50%). When you know that you have stage 4 or systemic metastasis, it doesn’t mean that your condition is very serious and there is no cure. Don’t give up treatment easily. The treatment of lymphoma is mainly systemic chemotherapy and radiotherapy. Li Kaifu’s treatment plan is that bendamustine (bendamustine) is combined with rituximab (rituximab, trade name: rituximab). Different from traditional chemotherapy drugs, rituximab is called "an artifact to accurately combat lymphoma". It is an anti-CD20 monoclonal antibody against malignant B lymphocytes, with good effect and little side effects, and it is a milestone in the treatment of lymphoma. 　

Since rituximab was listed in the United States in 1999, the 5-year survival rate of patients with diffuse large B-cell lymphoma has increased to 50%. Rituximab used to be a self-funded drug, which was expensive. Now it has been included in the scope of medical insurance reimbursement, which has enabled many cancer friends to enjoy the fruits of modern medical progress.　　

In addition, Kai-Fu Lee also tried many kinds.Natural therapyIn order to finally defeat cancer.

Keeping a good sleep is the most important thing. Staying up late for a long time may reduce the body’s immunity, and his lymphoma is a common cancer in the immune system. Therefore, after suffering from cancer, he made a schedule to protect his immunity. It is necessary to keep your mouth shut when disaster comes from your mouth. It is particularly important for cancer patients to keep their mouths shut, and maintaining good eating habits can better fight cancer. Kai-fu Lee suggested that everyone should eat more grains, beans, fruits and vegetables, and take a balanced intake. 3. Take your legs apart and exercise properly to inhibit cancer cells. Many studies have confirmed that exercise is beneficial to the rehabilitation of cancer patients and can reduce the risk of cancer recurrence after operation. However, it should be reminded that not all exercise is suitable for cancer patients, and it is suggested to use the principle of "not feeling tired". 4. Good attitude, get twice the result with half the effort When fighting cancer, it is very important to keep a good attitude, which has a great influence on cancer treatment.

Pancreatic cancer: steinman "tried medicine by himself", and the dendritic cell vaccine made him live for four and a half years!

　 Speaking of vaccines, everyone is actually familiar with them, except for the common hepatitis B vaccine and influenza vaccine, and the Covid-19 vaccine that we have vaccinated up to now. In fact, cancer vaccine is also a form of immunotherapy, which can prevent cancer from developing or kill existing tumors by stimulating or restoring the human immune system. In the 21st century, the high incidence of cancer has attracted the attention of the global medical community. As a prominent tumor vaccine, dendritic cell vaccine has been a research hotspot in this field. When it comes to dendritic cell vaccine, we have to mention a legendary figure-ralph steinman, winner of the 2011 Nobel Prize in Physiology or Medicine. 　　

ralph marvin steinman After the diagnosis of pancreatic cancer in 2007, steinman actively tried a therapeutic vaccine (DC vaccine) based on dendritic cells. With the help of this "cellular immunotherapy", his life was extended from the expected months to four and a half years.　 There is a rule in the Nobel Prize that they never give this prize to people who have passed away. However, ralph steinman broke this rule because he passed away quietly three days before receiving the call for winning the prize. Therefore, Staman is also called the most regrettable Nobel Prize winner.

　 0one　　Suffering from pancreatic cancer with a mortality rate of 95%, he devoted himself to the research of DC vaccine.

In 1973, steinman discovered dendritic cells in the spleen of mice, and put forward the concept of dendritic cells. In 2011, steinman shared the Nobel Prize in Physiology or Medicine with Jules Hoffman and Bruce Beutler for "discovering dendritic cells and their role in the acquired immune system".

Pancreatic cancer, which claimed steinman’s life, is one of the malignant tumors with the highest mortality rate at present. The mortality rate of this disease can reach 95% clinically, and it is very rare for patients who can survive for 5 years after being diagnosed with this disease (< 5%). There is no approved cancer vaccine for pancreatic cancer, and the prognosis is very poor. The survival time of advanced patients is weeks or months. The disease is usually treated with the cytotoxic drug gemcitabine. However, this treatment seems to be mainly used for palliative treatment of advanced pancreatic cancer, which can improve the quality of life and prolong the median survival time of 5 weeks. Most patients will soon develop resistance to this drug. Therefore, the indomitable Professor steinman tried to use dendritic cell vaccine to treat his pancreatic cancer. Dendritic cells are the main antigen presenting cells (APC) in the immune system. They process antigenic substances (for example, from invading bacteria and viruses, and from cancer cells) and present antigens on their surfaces to other types of immune cells, especially T cells. This leads to antigen-specific activation of T cells. Therefore, dendritic cells act as the main link between innate immune system and adaptive immune system.　

02　　After eight treatments, dendritic cell vaccine made him live for four and a half years!

　 Professor steinman tried eight experimental therapies, one at a time. For each of these treatments, he and his colleagues submitted a single-patient use agreement to the FDA and obtained the approval of the agency. In these treatments, there are three kinds of cancer vaccines, and steinman finally used the dendritic cell vaccine from his own tumor instead of the cell line. Patients with advanced pancreatic cancer usually have poor prognosis. The median survival time of locally advanced and metastatic pancreatic cancer (advanced pancreatic cancer accounts for more than 80% of individuals diagnosed with the disease) is about 10 months and 6 months respectively. For all stages of pancreatic cancer, the 1-year and 5-year relative survival rates were 25% and 6%, respectively. However, Dr. steinman’s life span has been extended from several months to four and a half years! Since then, the medical community has launched a craze for the research and development of dendritic cell vaccines, which has become a kind of immunotherapy with more research and development achievements in recent years. At present, the dendritic cell vaccines approved by the FDA and many clinical trials entering the third phase are worth looking forward to. Since 2010, exceptThe FDA approved the first dendritic cell vaccine Provenge(sipuleucel-T) for the treatment of refractory prostate cancer. Dendritic cell vaccine has achieved good results in all kinds of cancer. Such as brain tumor-DC VAX-L vaccine, melanoma-—TLPLDC vaccine, renal cancer-—ilixadencel vaccine, newly diagnosed glioblastoma-AV-GBM-1 vaccine, lung cancer-CCL 21-dendritic vaccine, breast cancer -Her2 pulsed dendritic cell vaccine, etc.Xiaobian will not go into details here.

Nasopharyngeal Carcinoma: After 33 proton treatments, Li Zongwei successfully returned to badminton.

　 As the uncrowned king of badminton in the world, Li Zongwei, a famous Malaysian badminton player, has a brilliant career, with three runners-up in the Olympic Games, four runners-up in the World Championships, one runner-up in the soup cup and one silver medal in the men’s singles in the Asian Games. However, on July 25, 2018, he met another more powerful opponent-nasopharyngeal cancer. According to Malaysian media reports, Li Zongwei suddenly announced his withdrawal from the World Badminton Championships and the Asian Games badminton competition, and was later confirmed to have early nasopharyngeal carcinoma in September. However, Li Zongwei was not defeated by the disease. After 33 proton treatments of 25 minutes each time for more than two months, the doctor said that all the cancer cells in his body had been eliminated. In October of the same year, after he announced the success of anti-cancer, he said that he would return to badminton in December. Perhaps Li Zongwei is not a "winner" in badminton. Although he has won numerous titles, he has never won a world championship, including a slightly dismal record against Lin Dan. This time, however, in the face of this "competition" with the same disease, he finally won. This win will be the greatest capital of his life. In terms of treatment, it is difficult to perform radical surgery because of the special location and unclear boundary of nasopharyngeal carcinoma, the deep and narrow nasopharyngeal cavity, and many important blood vessels, cranial nerves and lymphoid tissues around it. But nasopharyngeal carcinoma is sensitive to radiotherapy, Therefore, radiotherapy is the main treatment for nasopharyngeal carcinoma, especially proton therapy. As the "king" of "precision radiotherapy", it can not only show its talents, but also effectively prevent the side effects of radiotherapy.

Proton therapy is a "qualitative leap" in tumor radiation!

　 Proton therapy is to accelerate the nucleus of hydrogen atom (i.e. proton) which has lost electrons to about 70% of the speed of light by using cyclotron or synchrotron. After being accelerated by the accelerator, protons with positive charges become very penetrating ionizing radiation, which enters the human body at a very high speed, is guided by special-shaped equipment, and finally reaches the targeted tumor site. Because of its high speed, the chance of interaction with normal tissues or cells in the body is extremely low. When it reaches a specific part of the tumor, the speed suddenly decreases and stops, and the maximum energy is released, resulting in a "Bragg peak", which can kill cancer cells without causing damage to surrounding tissues and organs.

　 　

When tumors are directly adjacent to important organs or structures, such as spinal cord, optic nerve and heart, proton therapy can still effectively treat tumors while protecting the functions of these important organs or structures, which is impossible in conventional radiation therapy.

　

The high radiation dose is concentrated in the tumor site, and there is no/little dose in the surrounding normal tissues.

　 　　

　

Legend: The radiation of Intensity Modulated Proton Therapy (IMPT) is mainly concentrated around the focus of nasopharyngeal carcinoma, with little or no influence on the surrounding normal tissues, while the radiation area of Intensity Modulated Radiotherapy (IMRT) is large, covering the focus and surrounding normal tissues.

Melanoma: "cured" after 4 months, immunotherapy made Carter the "longest-lived president"

　 In August 2015, former US President Carter was diagnosed with malignant melanoma, and liver metastasis and brain metastasis have occurred, so he is an out-and-out terminal patient. But just four months later, at an event in December, 91-year-old Carter announced that he had just confirmed after a general examination that the lesions in his body had disappeared. 　

It is understood that Carter used comprehensive therapy. First, the visible tumor was surgically removed, then the intracranial tumor was treated by radiotherapy, and finally the PD-1 drug Keytruda of Merck was used. After the brain cancer cells disappeared, Carter said that he would continue to use Keytruda for treatment. This incident made immunotherapy popular all over the world overnight. PD-1/PD-L1 and CTLA-4 pathways are crucial to the immune system’s ability to control cancer growth. These pathways are often called immune checkpoints. Many cancers will use these ways to escape the immune system. Specific antibodies to immune checkpoint inhibitors can block these pathways to deal with cancer. Once the immune system can find and deal with cancer, it can stop or slow down the development of cancer. Having said that, I have to mention the biggest difference between immunotherapy and traditional treatment, that is The trailing effect of immunotherapy, that is, patients who benefit from immunotherapy can continuously obtain stable results and bring long-term survival.

This article is original for a cancer-free home, and it needs authorization to reprint.

　　Huawei-related topics are always one of the hot spots in the industry.

　　Recently, a chat record involving the dystocia of the first model of the Zhijie brand, which Chery cooperated with Huawei, quickly circulated on the Internet and continued to ferment. In the chat record, a netizen suspected of being a Chery employee directly pointed the finger at Huawei for the dystocia of Zhijie S7, and revealed that "the leader who has been working hard to promote cooperation with Huawei directly resigned."

　　Subsequently, the leader was confirmed as Han Biwen, deputy general manager of Chery Automobile Co., Ltd. and general manager of the manufacturing division. However, on January 31, the reason for Wang Chuan’s departure was denied by Chery’s spokesperson Jin Yibo: the cooperation between the two parties was smooth, and they were making every effort to promote the production and delivery of Zhijie S7, and they had invested more resources and would continue to deepen cooperation.

　　But this response does not seem to be recognized by the public.

　　The intellectual S7 is "far ahead" and "far away"

　　After questioning, M7 went against the trend and returned to the mainstream market after its listing, which made its new cooperation project Zhijie Automobile become the focus of public attention. However, in 2024, the delivery of the new M7 four-wheel drive version, the delayed delivery of Aouita 12 and the dystocia of Zhijie S7 made Huawei’s new models collectively face the delivery problem.

　　For the first two, whether it is CMO Li Pengcheng, vice president and chief marketing officer of Aouita Science and Technology, or all the suppliers visited by Gaspar, it is attributed to the fact that the sales of products far exceeded expectations, resulting in insufficient supply. "At present, the production capacity is climbing, and the supply shortage will be alleviated as soon as possible in the past two weeks." A practitioner who supplies the new M7 precursor parts in the world revealed to Gaspar.

　　However, compared with the sweet burden of the new M7 and Aouita 12, the intellectual S7 is still shrouded in gloom.

　　On January 15th, Zhijie Automobile issued a document on its official account, saying that the factory is making every effort to produce and ensure high-quality delivery. This subsidy is mainly for users who have made a decision between November 28th, 2023 and January 15th, 2024. They can enjoy the subsidy after waiting for more than 6 weeks, and they can get a maximum subsidy of 10,000 yuan in 200 yuan every day.

　　Previously, there had been a lot of rumors on related forums and social platforms that Zhijie S7 was delayed in delivery and not delivered in order. Just one week after the release of the above compensation plan, Gaspar learned from the relevant sales staff that the official promised delivery time has been extended from 6 weeks to 10-12 weeks.

　　On November 28th, 2023, Huawei released the first pure electric car-Zhijie S7 under the smart car selection business model, which is the first product of Zhijie brand and the first model of cooperation between Huawei and Chery under the smart car selection business model.

　　According to the latest news, as of the end of December, the large quantity of Zhijie S7 has exceeded 10,000, and the number of offline stores has exceeded 100 in a single day. However, according to the terminal data of Geshi Automobile Research Institute, in December 2023, the cumulative sales volume of Zhijie S7 nationwide was only 305, and according to the staff of Zhijie Automobile’s delivery center in Shanghai, there was only one centralized delivery in December last year, and there were no new cars afterwards.

　　Obviously, it seems difficult to copy and paste it on Zhijie S7 due to excessive sales and insufficient production capacity. You know, compared with the manufacturing strength of Cyrus, the new "Intelligent Networked Super Factory No.2" built by Chery has a planned annual production capacity of 500,000 vehicles, which makes it hard to believe that Zhijie S7 will be difficult to produce.

　　In this regard, the senior analyst of Gaspar Automotive Research Institute believes that instead of the high centralization of Huawei in software, it is more inclined to the imbalance of production rhythm between the two parties after the release of new cars, the yield of supply chain parts in mass production of new technologies and the insufficient preparation of the production line of the automobile factory are all reasons for the delay in mass production of Zhijie S7.

　　The rumor that "Huawei has no basic respect for Chery" may not be groundless. Some insiders pointed out to Geshi Automobile that in the car-making business, Huawei really wants to dominate the whole process of new cars, but in cooperation with enterprises with scale advantages such as Chery and Changan, they also don’t want to be only supporting roles, and conflicts in product dominance and management styles and cultures of different companies are inevitable.

　　The success of asking the world may be difficult to replicate.

　　As we all know, with more than 30 years of profound accumulation in the ICT field, Huawei has cut into the car track in three modes: standardized parts suppliers, HI mode and HarmonyOS Zhixing, and the cooperation has gone from shallow to deep.

　　Among them, HI mode is provided by Huawei with full-stack smart car solutions such as intelligent cockpit, intelligent driving and intelligent Che Yun, such as the cooperation of BAIC Extreme Fox and Aouita brand; In addition to providing parts and solutions, HarmonyOS Zhixing will also fully participate in product design, brand building, sales channels and other aspects, such as the cooperation with Cyrus, and so on.

　　According to Yu Chengdong’s plan, Huawei’s automobile business unit (Car BU) plans to make a profit in 2025, so as to change the situation that "Car BU is Huawei’s only loss-making business". To achieve this goal, it is necessary to ensure that the cumulative sales volume of HarmonyOS Zhixing and HI mode reaches 1 million vehicles.

　　It is worth noting that according to the terminal data of Geshi Automobile Research Institute, in 2023, the cumulative sales volume including Aouita 11/12, Wenjie M5/M7/M9 and Zhijie S7 was only 114,000.

　　This means that Huawei BU must accelerate the pace of implementation this year. On January 16th, the day after HarmonyOS Zhixing implemented the compensation scheme of Zhijie S7, a wholly-owned new company, Huawei Car BU, was formally established. On the same day, the joint venture between Huawei and Changan also made new progress. Changan Automobile revealed that the new joint venture between Changan and Huawei was tentatively named "Newcool".

　　As for Yu Chengdong, Huawei will also cooperate with BAIC and JAC respectively in HarmonyOS Zhixing business after consulting with the intellectual community. The brand of cooperation between Huawei and BAIC HarmonyOS Zhixing mode is determined as "enjoying the world", and the first model is positioned as a medium and large car, which will be officially released before the Beijing Auto Show in April; The brand of HarmonyOS Zhixing, which cooperates with Jianghuai, is designated as "Aojie", and the first car will be released in Q4, 2024, which is a million-level product.

　　According to the latest news, as of January 28th, the cumulative sales volume of vehicles in the car industry in January has exceeded 28,000, setting a new record for the highest monthly sales volume. According to the data on January 9th, the cumulative delivery volume of the new M7 has reached 48,552 vehicles, and the cumulative sales volume has exceeded 120,000 vehicles. It is worth mentioning that, in addition to the new M7, the two models of the AITO series, the M5 and M9, have also received much attention. With the launch of mass delivery of the M9 and the launch of the new SUV model M8, it is expected to further promote the sales of the M 9 brand to a new high.

　　Therefore, to a certain extent, S7, the first model of Zhijie brand, has become the key to whether Huawei’s HarmonyOS Zhixing model can win the cooperation between car companies.

　　However, in the view of senior analysts of Gaspar Automotive Research Institute, the core sales source of HarmonyOS Zhixing model in the future will still be the contribution of the products that have cooperated with Cyrus, and it is also Huawei’s most "obedient" and recognized partner in this model, and the products of other enterprises may not have much sales performance. "The delay in the delivery of the intelligent S7 will inevitably affect the user’s car purchase choice, which in turn will affect the confidence of cooperation between the two parties."

　　Zhu Huarong, the chairman of Changan Automobile, who established a new joint venture with Huawei, is even more outspoken in his resistance to HarmonyOS Zhixing. He stressed that Changan must have its own brand and choose Hi mode because it conforms to the national industrial policy. The implication is that under the HarmonyOS Zhixing model, the division of labor between Huawei and car companies is unclear, which may lead to problems in the protection of rights and interests in the process of users using cars.

　　There is a clearer positioning, which is the insistence of Changan Automobile, and I believe it is not just the insistence of Changan Automobile.

　　In tHis context, the above analysts believe that hi mode will still have enterprises to adopt cooperation, especially domestic car companies, mainly to complement their intelligent shortcomings and learn from the organization and management of Huawei IPD. In addition, Huawei Car BU Yinwang Technology Co., Ltd. has a very large room for growth in the future by binding car companies to create an "ASML model" in the smart car ecosystem.

　　As mentioned earlier, Huawei’s circle of friends continues to expand rapidly. If all goes well, it is not out of reach to achieve the goal of one million vehicles in 2025. However, the success of the world of inquiry has not made all brands resolutely hand over the dominant position like Cyrus, and the constant disputes in the intellectual world have made Huawei’s future in the last three "circles" full of uncertainty. How to balance the needs and cooperation of different car companies may become a more critical focus of Huawei HarmonyOS Zhixing in the future than expansion. （Garcia）

Produced jointly by Wenhuaren (Beijing) Culture Media Co., Ltd. and Fengxing Online, the highly anticipated short play "Clouds Going Up" will be officially launched on May 10th. With its unique world outlook of coexistence of ancient martial arts civilization and modern civilization, the play has attracted a large number of audiences’ attention. In this work, Shi Fei Da, a powerful actor, will play Wen Yu, the eldest brother of the three brothers and sisters of the Wen family, which has attracted strong attention from fans.

Shi Feida, who is 178cm tall and weighs 65kg, has a handsome appearance and unique temperament. He is a versatile actor with rich acting experience. As early as 2010, he partnered with Ni Ping, a famous actor and host, to host the Third China Artists Awards Ceremony in world artists association, USA, and won the Best Newcomer Award. This honor not only affirmed his hosting talent, but also predicted his infinite possibilities in the future.

While at school, he was lucky enough to participate in the film Far away Xilin Gol directed by the famous director Gao Feng, and he played Guo Qinglin (first hero), an educated youth in Beijing, and accumulated valuable performance experience. After graduation, he devoted himself to the shooting of many main melody films, constantly challenging himself and improving his acting skills.

In the anti-Japanese war film Sun Face directed by Xinyun Zhu in 2013, Shi Feida played Zhou Maosong, and his superb acting skills and solid lines were widely recognized in the industry. Whether it is the emotional expression of the role or the interpretation of the action play, he has shown excellent professionalism and acting talent.

In addition, Shi Feida’s performance in the film field is also quite eye-catching. His film works include Strange Crime, Qian Xuesen, Far-off Xilin Gol, Lost, Music and Whose Child. In these works, he created many characters with different personalities and distinct images, which showed his diversity and plasticity as an actor.

In the upcoming short play "Clouds Going Up", Shi Fei Da will play Wen Yu, the eldest brother of Wen Ji’s family, which is a role full of sense of justice and responsibility. In Yun Kaminooji, a world where ancient martial arts civilization and modern civilization coexist, he will lead his younger brothers and sisters to protect ancient martial arts civilization, maintain modern order and present a legendary heroic image for the audience.

Shi Feida said that he was very excited and looking forward to playing such a role. He believes that the story background and role setting of "Up in the Clouds" are very attractive, and he will devote himself to shaping the role and bring a brand-new and unforgettable performance to the audience. With the upcoming launch of Clouds Going Up, the audience are full of expectations for Shi Feida’s performance in the play. I believe that he will bring a double feast of vision and mind with superb acting skills and profound performance skills.

"Clouds Going Up" is not only a wonderful short play that combines ancient martial arts civilization and modern civilization, but also a masterpiece that shows the brilliance of human nature and heroic feelings. With the participation of many outstanding actors such as Shi Fei Da, the play will surely become the focus of the audience’s attention. Let’s look forward to the arrival of May 10th and witness the wonderful performance of Shi Feida in Clouds Up.

　　German scientists have discovered a magical chameleon subspecies in northern Madagascar. They are only the size of melon seeds and can lie on human fingers, which may be the smallest reptile on the earth.

　　The Bavarian National Zoo in Munich, Germany, said that they found two adult miniature chameleons, a female and a male, in northern Madagascar. Among them, the male is only 22 mm long, which is the smallest known reptile. The other female chameleon is a little bigger, but the total length is only 29 mm.

　　The researchers said that it is not clear why the species is so small, but perhaps similar to the "island effect", animals trapped on the island and with small habitats tend to evolve smaller bodies.

　　However, the living environment of this new species is worrying. The habitat of this chameleon has been destroyed by deforestation. Fortunately, in recent years, the government has planned a protected area in the local area, so they are lucky to survive.

When our career is stable and our income is gradually "well-off", our originally poor life has also changed a lot, and the car we once yearned for is no longer out of reach. The late car cost of plug-in hybrid is the point that its potential consumers pay more attention to. Let’s look down with Xiaobian.

Let’s take a look at the appearance of the Volvo XC60 plug-in hybrid. The Volvo XC60 plug-in hybrid front is avant-garde and looks more delicate. Headlights are very avant-garde, and the overall look has a certain sense of hierarchy. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, automatic steering, delayed closing and so on. Coming to the side of the car body, the size of the car body is 4708 mm * 1902 mm * 1656 mm. The car adopts sharp lines, and the side gives a very tough feeling. With large-sized thick-walled tires, smooth lines run through the whole side of the car. In the design of the rear end, the rear end looks more capable, and the taillights give people a very sharp feeling, and the shape is relatively hard.

Sitting in the car, the Volvo XC60 plug-in hybrid interior looks very comfortable, and the overall visual effect is very distinctive. The steering wheel of the car is very cute, made of leather, and the shape is very fighting. Take a look at the central control, with a 9-inch touch-sensitive LCD central control screen, which makes the interior style impressive and gives people a sense of simplicity and generosity. Finally, let’s take a look at the dashboard and seats. The car is equipped with a stylish dashboard with a sense of technology. The car adopts leather seats, and is equipped with functions such as electric adjustment with memory in the auxiliary seat, electric adjustment with memory in the seat, and seat proportion tilting, which further improves the comfort of the driver and passenger.

Next, look at the configuration. Volvo XC60 plug-in hybrid is equipped with car networking, driving mode selection, remote control key, rear wiper, traction control (ASR/TCS, etc.) and other configurations.

The moderate size of the car is a very suitable choice for many families, and the internal space is enough for daily use in families. As long as you really like it, it’s over. Go to the 4S shop and place an order.

　　People’s Daily Online, Beijing, May 13 (Yang Xi) Recently, the release of the main data of the seventh national census has aroused great concern from all walks of life. Some netizens found that the trend reflected by the census data published this time is inconsistent with that published in non-census years, so they raised some questions about individual data.

　　In this regard, the National Bureau of Statistics answered the above questions and related questions of population statistics.

　　How to count and publish population data?

　　At present, China’s demographic survey mainly has three ways:

　　The first is the national census, which is conducted once every ten years in the year when the mantissa meets "0", and the census data is published in China Census Data.

　　The second is the national 1% population sampling survey, which was conducted in the year when the mantissa met "5", and the survey data was published in the National 1% Population Sampling Survey Data.

　　Third, the national sample survey of population changes, the sample size accounts for about 1&permil of the total population; In addition to the census year and the sampling year of 1% population survey, it is conducted once a year, and the survey data are published in the Statistical Yearbook of China and the Statistical Yearbook of Population and Employment of China.

　　The main statistical indicators of the above three types of population data will be published in the annual data in the database of the National Bureau of Statistics.

　　Why is the trend reflected by census data inconsistent with that published in non-census years?

　　The population in non-census years is calculated according to the sampling survey data of that year. Due to the missing rate of sampling surveys in some years, there will be some deviations in the estimated population as a whole, and these deviations will continue to accumulate with the passage of time.

　　Carrying out the population census once every 10 years can comprehensively find out the number, structure and distribution of China’s population, let us know more clearly the development of China’s population in the past 10 years, and provide extremely valuable data for better studying population issues and formulating population-related policies.

　　So how to deal with this inconsistency? According to international practice and common practice, after the census, the annual data published between the two censuses are generally revised according to the census results, so as to reflect the population development track more truly and objectively. In the sixth national census and the just-concluded fourth national economic census, historical data were also revised according to census data. At present, this work is in progress, and the relevant data will be released on schedule after the revision is completed.

　　Is the population statistics based on household registration or residence?

　　At present, China’s population census and population survey are counted and summarized according to the resident population. The time standard for judging the permanent population is half a year, and the space standard is township, town and street.

　　The resident population is an important basic data for formulating the national economic and social development plan, evaluating the national economic production capacity, and evaluating the welfare level of residents. It has a wide range of applications, such as financial expenditure, urban construction, housing construction, allocation of public facilities, education investment, medical investment and public utility investment, etc., which need to be planned according to the size of the resident population.

　　The registered population refers to the registered population in a certain area, regardless of whether they go out or not, as long as they register their permanent residence in the public security household registration management department. The data of registered population is counted by the public security department. For a long time, China has established a set of perfect household registration statistics and management system, which has played an important role in social management.

　　How is the floating population data counted?

　　Floating population refers to the population whose residence is inconsistent with the township street where the household registration place is located, and who has been separated from the household registration place for half a year or more (excluding the separation of households within the municipal area). The survey indicators used to judge and reflect the floating population include: the place of registration, the place of residence at the time of investigation, the time of leaving the place of registration and the reasons for leaving the place of registration. The National Bureau of Statistics formulates a demographic survey system according to the Statistics Law of the People’s Republic of China, conducts demographic surveys on a regular basis, and publishes major demographic data such as permanent population, birth population, dead population, urban and rural population and floating population.

　　Line up for spicy food.

　　Tempting Gansu mala Tang.

　　"Bouquets of vegetables" are one after another, and enthusiastic diners are one after another. After Tianshui Mala Tang went out of the circle, this "sky-splashing flow" also began to flock to Lanzhou, and the passenger flow of major Mala Tang shops in the city continued to rise obviously. Embracing this wave of traffic dividends, on March 20th, famous local restaurants in Lanzhou took advantage of the situation to offer a new "Gansu Mala Tang" and add another fire with innovative dishes. Even the University of Science and Technology Beijing, thousands of miles away, issued an official announcement, "The campus canteen window, authentic Tianshui Mala Tang in Gansu, is officially launched"!

　　A Lanzhou hot spicy dip famous store huo Shang Jia huo

　　When visiting Lanzhou, Jin Lan Mala Tang in Anning District must be on the must-eat list.

　　At noon on March 19, looking at the endless diners, Ms. Chen, a citizen of Lanzhou, lamented: "Jin Lan Mala Tang, which is deeply loved on weekdays, has become more popular recently!" This is an old-fashioned Mala Tang shop in Lanzhou. The proprietress’s name is Wen Jinlan, and she is from Longnan, Gansu Province. She has been here for more than 20 years. After the hot spicy dip in Tianshui, more and more diners came here, and sometimes they even had to wait in line for an hour to eat.

　　In order to meet the huge passenger flow, it is normal for Wen Jinlan to get up early for nearly 20 hours every day. The reason why it is popular, in the view of the proprietress Wen Jinlan, is because of "popular taste, everyone likes it". The raw materials such as Gangu pepper, Wudu Dahongpao pepper, vermicelli specially customized from Dingxi and grain vinegar produced nearby have jointly contributed to the mouth-watering "spicy and hot".

　　"A large pot of vegetables, all kinds of ingredients wrapped in red juice, a spoonful of crisp sour radish, and the smell of oily spicy seeds between chopsticks directly hit the taste buds." Every meal, Yanji Mala Tang in Zhengning Road, Chengguan District, all the tables inside and outside the store are full. Many people ask, after more than 30 years of opening, people are so popular that there must be an exclusive secret recipe, right? Mr. Zeng, the boss, said frankly: "My wife and I are out-and-out Jianyang people in Sichuan. We have lived in Lanzhou for decades. We improved and adjusted the proportion of juice according to the tastes of local people, which reduced the hemp degree of pepper. It brings together Gansu local materials such as Dingxi Kuanfen and Gangu Chili, forming a unique flavor of Gansu Mala Tang. "

　　B Lanzhou local catering enterprises innovate dishes.

　　On March 20th, Duanji Hotel in Yantan, Lanzhou officially launched the new dish "Gansu Mala Tang". Yang Guoyan, Chairman of the Folk Food Committee of Longcai Association and Deputy General Manager of Lanzhou Duanji Catering Management Co., Ltd., told Benben News reporter: "In order to meet this wave of traffic, we have developed a new dish close to Tianshui Mala Tang, with ingredients such as Gangu Chili, Dingxi Kuanfen and Qin ‘an Zanthoxylum. As a Longcai hotel, our goal is to create a &lsquo; Ganwei hot spicy dip &rsquo; The alternative ingredients will be more extensive, adding lily, yak meat and so on. " Yang Guoyan said that many employees in the store are from Tianshui. Through repeated trial production for many days, this new product has been officially launched.

　　"After Tianshui Mala Tang is on fire, how can we seize this wave of traffic and continue to undertake this heat to Lanzhou? In fact, we still have to work hard on product innovation." Yang Guoyan said, "Gansu is more delicious than mala Tang, Wuwei &lsquo; Three sets of cars &rsquo; , Zhang Ye &lsquo; Stir-fry firecrackers &rsquo; , Longnan stirred up the group &hellip; &hellip; Longshang cuisine has a long history. How to make use of this mala Tang craze to make all kinds of snacks in Gansu known to more people and promote them to the whole country requires not only the help of the cultural tourism department, but also the joint efforts of the catering industry and other departments. "

　　C "Gansu Mala Tang" online orders skyrocketed.

　　According to the data of Meituan, since March, the search volume of keywords related to "Gansu Mala Tang" has increased by 18.5 times from last month, and the number of public comments has soared by 13.2 times. The take-away orders of Gansu Mala Tang increased 66 times from last month. Beijing, Xi ‘an, Jinan, Shanghai and Tianjin are the top five cities in search volume.

　　At the same time, the popularity of Tianshui Mala Tang has also driven the growth of local cultural tourism consumption. The booking volume of travel orders in Tianshui City, Gansu Province increased by 71.8% compared with the same period of last year. Among them, the order volume of hotels and homestays increased by 73.6% year-on-year, and the order volume related to scenic spots increased by 216.8% year-on-year. Maijishan Grottoes, Fuxi Temple, Maijishan Hot Springs, Xianrenya and Yuquan Temple are the top five scenic spots in terms of order volume. Shaanxi, Henan, Jiangsu, Guangdong, Ningxia, Beijing and Sichuan are the top provinces and cities in the source of off-site orders.

　　On various social platforms, many netizens called for authentic Gansu Mala Tang to be eaten in their hometown, and called on Tianshui people to open stores in their hometown. Some physical stores that see business opportunities are trying to seize the opportunity &hellip; &hellip;

　　Gansu Beijing Office, located in Beijing Feitian Mansion, has recently put up "Gansu Mala Tang", attracting many netizens to taste the punch card. And a female shopkeeper from Tianshui also decided to open a Gansu Mala Tang restaurant in Sanlitun, one of the hottest business districts in Beijing, which is expected to be officially opened in half a month.

　　On March 19th, University of Science and Technology Beijing issued a document saying that "Gansu Tianshui Mala Tang" will be launched in the school cafeteria at noon. In order to reflect the authenticity, the school emphasized that "soul juice" is all from Gansu, and it brings together two ingredients of Tianshui, namely Gangu pepper and Qin ‘an pepper. The potato powder is elastic and smooth, Gangu chili pepper is full of oil, and the most delicious thing is the intersection of fresh hemp and Qin ‘an pepper. In fact, as early as 2012, the school established a fixed-point assistance relationship with Qin ‘an County, Gansu Province, and purchased Qin ‘an pepper every year. This year, a new potato powder procurement project was added, and the canteen master went to the local area for research and study, bringing students a better experience.

　　Searching with "Gansu Mala Tang" as the key word through Tianyanchao platform, in the past three months, there have been more than 200 new Mala Tang shops in China. Among them, since February this year, there have been more than 150 newly opened Gansu Mala Tang shops in China. According to the data of Tianyancha Professional Edition, up to now, there are more than 9,600 mala Tang related enterprises in Gansu, while there are nearly 900 related enterprises in Tianshui City alone.

　　Text/Figure Benliu News Lanzhou Morning News reporter Xu Jingwen

Jing Zheng Fa [2018] No.30

District People’s governments, municipal government commissions, offices and bureaus, and municipal institutions:

　　In order to thoroughly implement the Supreme Leader’s Socialism with Chinese characteristics Thought in the New Era and the spirit of the 19th National Congress of the Communist Party of China, fully implement the decision-making arrangements of the CPC Central Committee and the State Council on stabilizing employment, take multiple measures simultaneously and comprehensively, and ensure the smooth completion of the employment objectives and tasks in this city and the sustained and stable employment situation in the current and future period, according to the spirit of "Several Opinions of the State Council on Doing a Good Job in Promoting Employment in the Current and Future Period" (Guo Fa [2018] No.39), combined with the actual situation, the following implementation opinions are put forward:

　　First, support the stable development of enterprises

　　(1) Increase the support for stabilizing posts. Since January 1, 2019, 50% of the unemployment insurance premium actually paid in the previous year can be returned to the insured enterprises that have not laid off employees or laid off fewer employees. From January 1 to December 31, 2019, for the insured enterprises that face temporary production and operation difficulties and are expected to recover, and insist on not laying off employees or reducing layoffs, the return standard can be determined according to the monthly per capita unemployment insurance premium and the number of insured employees in the previous year of this city for six months.

　　(2) Continuously optimize financial services. Improve the policy financing guarantee system, increase the scale of financing guarantee for small and micro enterprises, guide more financial resources to support entrepreneurial employment, and further alleviate the problem of financing difficulties for small and micro enterprises. Banks and other institutions that have made outstanding achievements in the work of business guarantee loans may be rewarded according to 1% of the newly issued business guarantee loans in that year.

　　(3) Guiding and stabilizing labor relations. Strengthen the supervision and management of enterprises’ implementation of the labor contract system and the collective contract system, encourage enterprises to carry out collective consultations with employees, urge enterprises to protect the legitimate rights and interests of employees according to law, further build harmonious labor relations and stabilize employment.

　　Second, encourage entrepreneurship to drive employment

　　(four) increase the support for the discount of business guarantee loans. Small and micro enterprises registered and operated in this city, when the number of newly recruited people who meet the application conditions for business start-up guarantee loans reached 25% of the existing employees (15% for enterprises with more than 100 employees) and signed labor contracts with them for more than one year, can apply for business start-up guarantee loans with a maximum of 3 million yuan according to the standards of the number of recruited people and the amount of each person not exceeding 150,000 yuan, and the discount funds will be borne by the finance. Increase the maximum amount of personal small convenient loans from 100,000 yuan to 150,000 yuan.

　　(5) Strengthen the construction of entrepreneurial carriers. Accelerate the construction of business incubation carriers for key groups and provide low-cost venue support, guidance services and policy support for entrepreneurs; According to the number of entities, the incubation effect and the employment effect, the business incubation base will be rewarded. Support areas with stable employment pressure to provide free business venues for unemployed people to start their own businesses. Strengthen the construction of the "Growth Enterprise Market for College Students" in this city’s regional equity market, and provide professional services such as project incubation, capital docking, equity custody, training and guidance for entrepreneurial enterprises.

　　Third, carry out skills training to improve the quality of employment

　　(six) support enterprises in difficulty to carry out skills training for employees. From January 1 to December 31, 2019, difficult enterprises can use the education funds of enterprise employees to carry out on-the-job training for employees by themselves or by entrusting institutions with corresponding training qualifications in this city. Employees who have obtained corresponding vocational qualification certificates or vocational skill grade certificates after training shall be subsidized by their enterprises according to 50% of the subsidy standard for technical skill upgrading; To carry out non-level skills training and each person’s training time is not less than 20 class hours, and give enterprise subsidies according to the standard of 500 yuan per person.

　　(seven) to encourage workers to improve their professional skills. From January 1, 2019 to December 31, 2020, the application conditions for technical skills upgrading subsidies in this city were relaxed from employees of enterprises who participated in unemployment insurance for more than 3 years to those who participated in insurance for more than 1 year; Persons with employment difficulties in urban and rural areas in this city who have not received unemployment insurance benefits can enjoy cost of living allowance, which is not less than that in 35 yuan, per person per day during the training period, and cost of living allowance policy only enjoys it once per person per year.

　　(eight) to mobilize social forces to participate in vocational training. Support all kinds of vocational colleges (including technical colleges), ordinary colleges and universities, vocational training institutions and qualified enterprises to undertake vocational skills training or entrepreneurship training for unemployed people and rural migrant workers, and give vocational training subsidies according to regulations. The subsidy standard is determined according to the training cost, training duration, market demand and obtaining relevant certificates. Timely study, adjust and enrich the catalogue of vocational training subsidies, and expand the benefits of policies.

　　Fourth, accurate policy to help employment

　　(nine) to expand the scope of employment trainee subsidies. From January 1, 2019, the scope of employment trainee subsidies will be expanded from unemployed college graduates who have left school to registered unemployed people aged 16-24 and rural laborers who have transferred employment registration; Organize them to participate in employment internships for no more than 12 months, give employment internship subsidies according to regulations, and appropriately raise the subsidy standards.

　　(ten) to improve the employer’s post subsidy standards. Employers will be encouraged to recruit people with employment difficulties in urban and rural areas, retired soldiers and laid-off workers from enterprises, and the post subsidy standard will be raised from 5,000 yuan per person per year to 8,000 yuan per person per year.

　　(eleven) to promote the employment of rural labor. Vigorously develop industrial projects with quick results and high returns to help rural laborers find jobs nearby. Encourage outstanding young people to return to their hometowns to start businesses and promote farmers’ employment. Broaden the channels for rural labor to transfer employment, support rural labor who are willing to go out for employment in urban public service posts, and implement relevant policies such as post subsidies and social insurance subsidies. Give full play to the role of rural public welfare posts and enhance the ability to provide care for rural people with employment difficulties.

　　V. Optimizing services to boost employment

　　(twelve) the implementation of permanent service. Unemployed people in this city and rural laborers who require the transfer of employment can apply for unemployment registration, transfer of employment registration and other businesses in the social security offices in the streets (towns) of their permanent residence, enjoy employment and entrepreneurship services nearby, and apply for employment and entrepreneurship support policies at the municipal level and in the districts where their permanent residence is located. People with employment difficulties in urban and rural areas can receive employment assistance in their permanent residence.

　　(13) Improve service quality. Actively use the "internet plus" model, build a network service platform for employment and entrepreneurship, promote departmental information sharing, streamline work links, and reduce application materials, so that "information runs more and people run less errands". Actively carry out policy propaganda, announce the policy list, bidding process, subsidy standard, service organization and contact information, supervise the complaint telephone number to the society, go deep into enterprises to preach policies, understand difficulties, solve problems, do a good job of helping, and promote the implementation of various employment policies and services.

　　(fourteen) to ensure the basic livelihood of the people in need. We will fully implement the unemployment insurance system and steadily raise the level of unemployment insurance benefits. A temporary living allowance of 3,000 yuan will be given to registered unemployed people who have difficulties in life and do not meet the conditions for receiving unemployment insurance benefits. We will integrate urban subsistence allowances, rural subsistence allowances, and low-income family identification systems, expand the scope of assistance, lower the threshold for assistance, and timely include families that meet the minimum living guarantee conditions into the minimum living guarantee scope. Improve the city’s temporary assistance system, give temporary assistance to qualified personnel, and help people in need to get out of trouble.

　　Sixth, improve the safeguard mechanism

　　(15) Strengthen organizational leadership. Give full play to the role of the municipal social security and employment work leading group, improve the working mechanism, and make overall plans for the analysis, policy formulation, guidance and inspection of the city’s employment situation. The relevant municipal departments and district governments should earnestly assume the main responsibility of promoting employment, strengthen communication and close cooperation, and do their best to promote employment.

　　(sixteen) to strengthen publicity and guidance. Guide enterprises to stabilize employees’ employment through transformation, training and job transfer, and support "double innovation"; Guide workers to establish a correct concept of employment, actively improve their employment skills, and realize employment and entrepreneurship through their own efforts. It is necessary to mobilize the forces of all sectors of society to form a joint force to promote employment.

　　(seventeen) optimize the financial security. Comprehensively sort out the existing capital projects that guarantee basic living, promote employment and stabilize employment, and on the basis of maintaining policy continuity and stability, merge and simplify the capital projects and use methods to improve the efficiency of capital use. Strictly implement the real-name management of employment assistance targets and effectively ensure the safe operation of funds.

the people’s government of beijing city

December 20, 2018

BA.4 and BA.5, the new branches of Omicron with stronger communication power, have recently attracted attention. The new branch has triggered a new infection peak in South Africa, and the Portuguese National Institute of Health also estimates that its growth advantage is 13% more than that of BA.2.

Screenshots from the nextstrain website show that the different Omicron branches represented by yellow, orange and red are iterating rapidly within half a year, and the new branches represented by orange and red are also expanding in the cracks.

Screenshot of nextstrain website. According to the uploaded sequencing data, since December last year, the mainstream branches in Omicron have gradually changed from BA.1 (shown as 21K) to BA.2 (shown as 21L) to BA2.12.1 (shown as 22C), and the area occupied by new branches is also expanding.

The new branches of Omicron are frequent. Is the current COVID-19 vaccine still effective? Do the branches BA.2 and BA.5 need their own vaccines? Should the update of COVID-19 vaccine keep up with the variation of virus? How to keep up with the virus mutation? With the above questions, the reporter of Science and Technology Daily contacted and interviewed a number of industry experts.

Is the current vaccine still effective?

Does the mutation branch in Omicron constantly trigger new infection peaks, which means that the current COVID-19 vaccine will be invalid?

Authoritative experts in the industry responded to the Science and Technology Daily reporter and said: "Current vaccines can still provide the most basic protection in ensuring the reduction of severe illness and death.. The epidemic in COVID-19 has been going on for two and a half years. At present, it seems that there is no possibility for Covid-19 to achieve zero infection through vaccination. COVID-19 vaccine can ensure the effect of reducing infection and avoiding serious illness and death. "

Regarding the role of the current vaccine in epidemic prevention and control, the person in charge of vaccine-related production enterprises in COVID-19 holds the same view: "The existing vaccine is no problem in preventing severe illness and death at present, but it will not be 100% anti-infection."

Many statistics or research results from the real world show that the current vaccine plays a significant role in preventing severe illness and death. For example, the latest data in Hong Kong (as of May 25th) showed that the mortality rate of those infected in Omicron who were not vaccinated was 3.04%, while the mortality rate of those infected with three doses of vaccine dropped significantly to 0.04%.

Do the branches BA.2 and BA.5 all need their own vaccines?

According to WHO’s latest weekly report on epidemiological progress in COVID-19 (May 25th),Omicron BA.2 and its progeny pedigree (BA.2.X) have become the main popular variants in the world.At present, the relative proportions of BA.2.X, BA.4 and BA.5 are 94%, 0.8% and 1% respectively.

This shows that during the evolution of Omicron mutant, the branch BA.1 is disappearing. However, the reporter learned that at present, most vaccines against Omicron in China are designed and developed for BA.1.

Whether it is necessary to develop new vaccines for new branches, the industry generally judges from the perspective of vaccine protection: if the activity of neutralizing antibodies produced by the original vaccines against mutant strains is greatly reduced, it is necessary to develop new vaccines; If it still has a good neutralizing effect on the mutant, there is no need to develop a new vaccine.

Although Omicron strain mutates rapidly and different branches appear, butNew vaccines will not be introduced for each branch, and there is no need to do so.. Relevant experts reminded: "If you continue to monitor, you will find that many mutations will disappear soon."

Can vaccine update keep up with virus iteration?

In the technical route of vaccine development in COVID-19, the design cycle of mRNA vaccine is short. On the basis of a mature platform, the design can be completed within 7 days, and the preclinical trials including animal experiments can be completed in about one month.

Industry experts engaged in the research and development of mRNA vaccine said that for the variant branch, the mRNA vaccine does not need to obtain the strain, but only needs to optimize the vaccine sequence according to the variant sequence and test the expression efficiency, and then pre-clinical trials can be carried out. Covid-19 Omicron mutant mRNA vaccine, developed by Suzhou Aibo Bio, China, has been approved for clinical research in UAE.

In response to virus variation, the technical route of inactivated vaccine can also complete the preclinical study of new strains in a short time by establishing an emergency system. The reporter previously learned that it can be advanced to the clinical trial application stage about 2 months after obtaining the new strain.

Keep up with the variation, can COVID-19’s vaccine market learn from the "flu model"

In order to cope with the frequent mutation of viruses, there are precedents for vaccine updates to follow closely. For example, the influenza virus vaccine is recommended by WHO every year, and countries produce new influenza vaccines accordingly.

In order to keep up with the variation in Covid-19, can the "flu model" be used for reference in the marketing of vaccines in COVID-19?

“It is estimated that the future development of COVID-19 vaccine needs to adopt the influenza model.The authoritative experts mentioned above responded, but WHO is unable to recommend mainstream strains through monitoring now, because the pandemic is not over yet.

Another advantage of the "flu model" is that it greatly shortens the time to market for new vaccines. Because there is no need for re-approval, its batch issuance system can effectively shorten the period from vaccine development to marketing. Experts in the industry said that after polishing and construction, various technical routes and platforms have gradually matured, the research and development speed has been accelerated, and the production process has been stable.If the "flu model" can be adopted in the development and marketing of vaccines in COVID-19, the time to market for new vaccines will be greatly shortened.

WHO has revealed some unexpected phenomena in its weekly epidemiological report: available data show that BA.4, BA.5 and BA.2.12.1 spread faster in countries where BA.1 was once prevalent, but less in countries where BA.2 was prevalent; The vaccination degree of each country may have an impact on the popularity of the new branch of Omicron. Visible,Covid-19 mutation and vaccine immunogenicity are mutually causal and widely related, and updating the vaccine in time may have an impact on virus mutation.

Source: Science and Technology Daily

Original title: "Omicron iterates fast, is it necessary to be" anxious "about the vaccine? 》

Read the original text

　　Yangguang. com BeijingsixmoonfiveJapan News (Reporter Sun Bingjie) Recently, a new type of Internet has emerged in Shandong and Fujian.+Home-based medical model-"shared nurses" has aroused public discussion. This one is connected to the Internet.+The new medical model of hitchhiking not only brings convenience to patients, but also causes social doubts about its safety. National Health Commission, as the competent department, responded a few days ago and will summarize the experience of "sharing nurses" in various places to guide the standardized development.

　　"shared nurses": a win-win situation for nurses and patients?

　　Bike-sharing, familiar with the public, etc.APPSimilarly, turn on the phone.APPChoose the service you need, place an order, wait for the platform to screen, and you can enjoy the services provided by nurses or doctors in just ten minutes. This is a "shared nurse" model popular in Jinan, Shandong and other places recently.

　　"shared nurse"APPWhat services can you provide? The reporter downloaded an earlier one with the words "shared nurse" on the mobile phone.APPBesides routine injections, infusions, blood collection, etc., its homepage can also provide services such as catheterization, enema, stitches removal and maternal and child care.

　　

　　This new type of "Internet"+The mode of "home care" is being welcomed by many users, such as Ms. Wan Juan in Beijing.APPA loyal user of. She told reporters that her family is old and young, and she rarely has time to go to the hospital.APPSolved her "trouble" to a great extent. "I have to queue up when I go to the hospital to register. The elderly and children at home are uncomfortable. I now make an appointment with doctors and nurses directly."

　　At present, the shared nurses launched by various platformsappThere is little difference in functions, mainly providing on-site service for nurses. In addition to the top three hospitals, some nurses come from outpatient departments of primary hospitals. The service items are varied, but mainly include injection and infusion, dressing change and maternal and child care.

　　Compared with public hospitals, the reporter noticed that nurses were shared.APPIt is generally expensive in price. Take basic services such as infusion and injection as an example. Most of themAPPOn-site service price is at150About yuan, more than hourly billing. According to the price of medical services in public hospitals in Beijing(2017edition),Adult outpatient intravenous infusion general public hospital price insevenYuan or so, only this one is close.twentyTimes.

　　However, in the view of employee Zhao Fei, the current pricing is still in the "acceptable range" compared with the cost of patients queuing in the hospital. And the shared nurse model can not only provide convenience for patients, but also give patients and nurses appropriate subsidies, which can increase the income of nurses.

　　"Now nurses pay more, but their income is not ideal. In particular, some nurses are too old to work at night, and theseAPPIt provides them with opportunities to realize their skills and increase their income. Yang Jie, a nurse in a hospital in Xicheng District, Beijing, told reporters.

　　"Aging" gives birth to the demand for home care

　　In fact, shared nursesAPPIt is not the first time that it has appeared. The upsurge of sharing economy in recent two years has also made the medical field the next outlet. Huge nursing demand and professional nursing force through "Internet"+"Shared nurses" are entering the families of ordinary people.

　　The latest statistics of the National Office for Ageing, as of2017At the end of 2008, the whole country60The number of elderly people over the age of2.4Billion, accounting for the proportion of the total population.17.3%, average nearfourIndividual labor supportoneAn old man. Many elderly people suffer from chronic diseases and need regular health care; Among the hospitalized patients, at least20%~30%% of patients still need nursing after discharge.

　　There is a strong demand for nurses’ home service. Mobile nursing platform provides opportunities for nurses to realize their skills. While "shared nurses" seem to be "win-win", the unsafe factors can not be ignored, mainly focusing on nurse qualifications, medical safety and so on.

　　According to National Health Commission2008The Measures for the Administration of Nurses’ Professional Registration, which was implemented in, stipulates that nurses can only engage in nursing work according to the registered practice place after obtaining the Nurse’s Practice Certificate through practice registration. According to the reporter’s understanding from National Health Commission, at present, except for Beijing, Tianjin and Guangdong, which are pilot areas for regional registration of nurses, nurses in most other provinces have no multi-point qualification.

　　"This means that the on-site service is actually carried out outside the registered practice place and is suspected of illegal practice." Analysis of Zhou Xuefeng, a lawyer of Beijing Jingshi Law Firm.

　　In addition, how to avoid the medical risks in the nurse’s home service center? It is the key to whether the "shared nurse" platform is reliable. The reporter noticed that the current shared nursesAPPFor patients with higher risks, they will generally not take orders, and nurses will also choose orders with lower risks. Yang Jie, who has many years of nursing experience, admits that the biggest risk of door-to-door infusion lies in its uncontrollable nature, and patients may have adverse reactions during infusion. The patients’ families lack emergency rescue equipment, "not only the patients will be very dangerous, but also the disputes between doctors and patients will be difficult to sort out."

　　Relevant policies are on the way.

　　this yearfourmoon28On April 20, the General Office of the State Council officially released "On Promoting the Internet"+Opinions on the development of medical health. Require a sound "Internet"+Medical health "service system. Promote the integration of Internet and medical and health services from the aspects of medical treatment, public health, family doctor signing, drug supply guarantee, medical insurance settlement, medical education, popular science and artificial intelligence application. It covers many aspects of medical treatment, medicine and medical insurance.

　　In an interview with a reporter from the Central Broadcasting Bureau, the relevant departments of National Health Commission pointed out that some provinces and cities with conditions have explored the "shared nurse" door-to-door service, which has solved the problem of the elderly and patients with mobility difficulties, brought convenience to the people, and is an exploration of nursing service entering the family.

　　According to the forecast of the World Health Organization,2050In, China will have.35%The population of more than60Years old, which means that China is also facing strong aging pressure under the background of building a well-off society in an all-round way. In Zhao Fei’s view, aging+The limited medical resources have created many urgent needs for Chinese to see a doctor at home. "Although the’ shared nurse’ has some flaws, it has responded to some extent.The basic desire of "seeing a doctor at home". Wu Zhipan, a professor at Peking University, said, "Most norm makers are facing the Internet.+"Mode, it is inevitable to behave behind some, should set aside time. "

　　Regarding whether it is legal for nurses to sign contracts with the online platform, the relevant authorities said in an interview that the multi-point practice of signing online platforms and physical medical institutions is not the same, but there is no relevant policy. National Health Commission said that the next step will be to gradually revise and improve the policies related to nurse practice management on the basis of summing up the pilot experience, combining with the promotion of graded diagnosis and treatment and the continuous deepening of medical reform. At the same time, further implement the "General Office of the State Council on promoting the Internet"+Opinions on the development of medical health, combined with the experience of exploring and developing "shared nurses" in various places, guides standardized development to meet the diversified and multi-level health needs of the public.