Empty cars are overloaded? There are many problems behind "light goods"

  CCTV News:Pay attention to a kind of truck that you will see in the city — — Blue brand light goods are light trucks with blue license plates. Compared with medium and heavy trucks with yellow cards, some cities in China have no restrictions on blue light goods. Since January 1st this year, the transportation department has also cancelled the freight qualification certificate and vehicle operation certificate of blue light goods, and drivers can drive as long as they have a driver’s license for small cars. The data shows that in 2018, the national sales volume of light trucks was nearly 400,000 units. In the first quarter of this year, the sales volume increased by more than 10% year-on-year. However, light goods are light, that is, cars are relatively light, and the goods pulled must not be too heavy. However, people who buy trucks generally want to pull more goods to earn money. In this way, some people secretly came up with a way to produce light trucks that can pull more goods, and many people bought them. However, there were also many subsequent troubles.

  It is "annoying" to buy a car and run on the road.

  The 38-year-old Leevane Hsiung’s hometown is in northern Shaanxi. At the beginning of this year, he went to Xi ‘an. At the suggestion of a friend, he bought a truck and started running transportation. After running for a while, Li Wenxiong discovered that what he was doing was worrying.

  Running transportation was a serious business, but how did it become a thief? Leevane Hsiung said that the problem lies in the weight of this truck. He bought a light truck, the length of which must be limited to 4.2 meters, and it can hang the same blue brand as ordinary cars, so the industry also calls this kind of car 4.2 m blue brand light. According to the regulations, in addition to limiting the length, light trucks also limit the total mass, that is, the total cargo weight, which can not exceed 4.5 tons at most. For this truck in Leevane Hsiung, the door and driving license are marked with a total mass of 4,495 kilograms, that is to say, after loading the goods, the total cargo weight can not exceed 4.495 tons. But Leevane Hsiung said, this label is a complete cover.

  Leevane Hsiung, the owner of the truck, has a self-weight of 4.2 tons. The total weight limit of the truck is 4.495 tons, minus 4.2 tons, only 300 kilograms can be pulled. There are three people in the cab of this car. If you sit on two people, I’m sorry, maybe you don’t want to pull the goods.

  The marked weight is 2.565 tons and the actual weight is 4.32 tons.

  However, the reporter noticed that the nameplate and driving license of Leevane Hsiung vehicles showed that the kerb quality of this truck, that is, its self-weight was 2.565 tons. How could Leevane Hsiung say that its actual self-weight was more than 4 tons? Facing the reporter’s question, Leevane Hsiung drove an empty car and randomly found a weighing station.

  Indeed, the weighing shows that the actual weight of the empty truck has reached 4.32 tons, and this weighing is only under the condition that the fuel tank is half full. Leevane Hsiung said that when running and transporting on the road, the fuel tank was filled with 70 kilograms and the water tank was filled with 200 kilograms. In this way, even if one kilogram of goods was not pulled, it was already overloaded. It’s not just Leevane Hsiung who encounters this dilemma. It’s another owner of Xi ‘an, Wang Xiangdong. This is a blue brand light truck purchased by Wang Xiangdong at the end of 2018, produced by Sichuan Nanjun Automobile Group. The maximum total weight limit of goods marked on the truck door and driving license is 4.495 tons. What’s the actual situation?

  The truck’s self-weight marked on the certificate and driving license is 2.72 tons, but the actual self-weight has reached 5.8 tons, which is also inconsistent with the real situation. According to the tonnage limit of light trucks, even if all the fuel tanks and water tanks are removed, it is overloaded.

  During the interview, the reporter just caught up with Wang Xiangdong and bought a new blue brand light truck, which is the Dexuan X9 dump truck produced by a local enterprise in Shaanxi. The certificate shows that the vehicle weighs 2,600 kilograms, but the actual weight is far more than that.

  Since there is a problem with the vehicle’s own load, why do car owners buy such vehicles?

  The car owners are willing to fight for the moment.

  Small car, flexibility and freedom, convenient access to the city, suitable for urban distribution and low cost, all these advantages make light trucks popular, but they also make some people think badly of temporary benefits. Insiders told reporters that the original positioning of this light truck was to transport lightweight goods such as daily necessities and household appliances, so the self-weight was low. However, in order to seize the transportation market, some automobile manufacturers violate the announcement in actual production, and increase the load capacity of vehicles by weighting them, so as to pull more goods.

  In addition to manufacturing, vehicle registration and registration, relevant laws and regulations also have clear requirements for technical parameters of motor vehicles. The motor vehicle registration regulations revised and issued by the public security department in 2012 clearly pointed out that the relevant technical data of motor vehicles are inconsistent with the announcement data; Not to apply for registration. However, how do the owners of these vehicles with inconsistent self-weight and actual self-weight register and get the license plate?

  According to the owner, in fact, when buying a car, both parties are tacitly aware that the owner pays the money and the salesperson is responsible for licensing. Take Wang Xiangdong as an example, when buying this Dexuan X9 dump truck, in addition to the normal car payment, it also paid 2,500 yuan as the license fee.

  Not only this sales company, but also the reporter interviewed randomly in the largest light truck sales market in Xi ‘an, and all the salespeople they contacted gave a promise to get on the card.

  On-line testing date must be "exquisite" on Saturday.

  Why did it go online on Saturday? The salesperson did not disclose it. Is it really what they said? The reporter decided to follow Wang Xiangdong’s field investigation. About ten days after getting the new car back, the salesperson called and asked Wang Xiangdong to go online for testing on April 27th, and said that all the materials had been handed over to the intermediary and the relationship had been coordinated. Sure enough, it is Saturday. Early the next morning, Wang Xiangdong came to the inspection station designated by the sales staff, Shaanxi Yongzhi Motor Vehicle Inspection Station. There was already a long queue at the door, all of which were blue brand light vehicles similar to those in Wang Xiangdong. Wang Xiangdong got through to the intermediary.

  After a while, the intermediary called again. Wang Xiangdong pulled into the testing station yard and was greeted by a man in overalls.

  After confirming the basic information of the owner’s name and frame number, the man left a piece of material and opened it. Both the reporter and Wang Xiangdong were taken aback. It turned out that this was a pre-filled inspection list, and the kerb quality was self-weight. It was 2600kg, dated April 26th, one day earlier than the inspection date. According to the regulations, if a motor vehicle wants to be registered, it must pass the vehicle inspection, and the kerb quality of the truck is its own weight, which is a mandatory item. However, in Shaanxi Yongzhi Motor Vehicle Inspection Station, there was no inspection at all, so Wang Xiangdong got the inspection record sheet, and it was also a premature delivery certificate.

  After the initial inspection, there was a re-inspection. On April 29th, the reporter and Wang Xiangdong came to the inspection station again.

  The initial inspection of fraud and re-inspection do not check the weight.

  In this way, the truck successfully passed the so-called test and got the license plate and driving license. According to the regulations, the inspection agencies and the traffic management departments of public security organs should conduct supervision and inspection through remote audit, spot check and file review. An insider who used to be in charge of technical work at a testing station in Shaanxi told reporters that under normal circumstances, testing institutions should rest in Japan on Saturday, and choosing such a time period to license the problem vehicles is actually a tacit understanding reached between the regulatory authorities and testing institutions.

  If there is a problem in many links, the car will be checked on the road.

  The lack of supervision in the production process, the tacit understanding of truck owners and sales personnel, and the open cheating of testing institutions have made these problem vehicles drive on the road. However, the inherent problem of empty cars being overweight makes these vehicles face punishment all the time. During the interview, the light car originally purchased by Wang Xiangdong was seized by the traffic police because it was overloaded.

  It turns out that this truck in Wang Xiangdong can only pull 1.58 tons of goods according to regulations, but when the traffic police seized it, his car pulled nearly 14 tons of goods, which was seriously overloaded.

  After paying the fine, Wang Xiangdong drove the truck that was overloaded when it was empty. For him, only by continuing to run fast can he make up for the loss. Overloading, punishment and overloading, shippers are in this vicious circle every day, which also poses a great threat to the vehicle itself and road safety.

  Safety is no small matter "light goods" must be light.

  Professionals told reporters that, as we said just now, these vehicles whose actual weight is higher than the announced weight and are illegally produced and licensed are called "big tons and small labels" by people in the industry. Some car companies regard light goods as a selling point, and they have already exceeded the tonnage limit before leaving the factory. This is an open "secret" in the industry, which has spawned a gray interest chain of forging data and illegally licensing. The country has a series of laws, regulations and standards for trucks, from manufacturing, registration to road transportation. Its primary purpose is to ensure safety, vehicle safety, pedestrians safety and you and me safety. However, in the face of interests, security has been forgotten, supervision has become a decoration, and the system has become a dead letter. In order to change this distorted situation, it is necessary for all departments to work together, especially from the production and registration links, establish a traceability and backward investigation mechanism, strictly supervise and seriously pursue responsibility, create a safe travel environment, and let "light goods" really travel lightly.

Striving spring | Cultivate a good plant and a fertile field.

  Changchun, China, March 11 (Reporter Guo Dongyu) How important is a good seed for food production?

  "Good seeds, good rain and good moisture can make us look forward to a bumper harvest year." Han Fengxiang of Fenghuangshan Agricultural Machinery Farmers’ Professional Cooperative in Lishu County, Siping City, Jilin Province said.

  "The contribution rate of excellent varieties to grain production has reached more than 45%, which plays a vital role in national food security." Zhang Zhijun, a researcher at the Corn Research Institute of Jilin Academy of Agricultural Sciences, said.

  "I have a dream, buried in the soil, convinced that it is different. Light gives it hope, rain nourishes it and grows with the seeds. " Yuan Longping, the father of hybrid rice, said.

  A small seed, one tied to the people’s rice bowl and the other tied to the national strategy (photo by Yang Guangwang)

  This year, the No.1 Document of the Central Committee proposed that the seed industry should be revitalized in depth, the pace of industrialization of corn and soybean biological breeding should be accelerated, the pilot scope should be expanded in an orderly manner, and planting management should be standardized.

  Recently, the reporter walked into Gongzhuling City, the founding unit of the National Modern Seed Industry Park and a national-level rice seed production county, to see how Jilin people on the black land grasped the "core" of grain.

  Organic fertilizer "waits" for the next field (photo by Yang Guangwang)

  In the more than 20,000 mu seed field of Hongxiang Seed Industry Co., Ltd. (hereinafter referred to as "Hongxiang Seed Industry") in Gongzhuling City, the land has been turned over and the organic fertilizer has been piled up at the edge of the field. "This seed production base was transferred last year. We used the method of black land protection to produce seeds. After a year of practice, the seed quality is very good." He Wei, general manager of Hongxiang Seed Industry, said.

  Walking into the seed cultivation room, a fresh new green brings ying ying spring. "This is our trial variety and we are testing the emergence rate." He Wei said, "The seedlings in this germination box grew the day before yesterday, and each leaf of them contains a lot of information, which is very important for us breeders." Here, enterprises invest about 50 million yuan in maize breeding every year. "We carefully selected the seeds and planted them in the experimental field. Through the growth and yield, we found those plants with less diseases, lodging resistance and high yield."

  A piece of new green "nurtures" the hope of a bumper harvest (photo by Yang Guangwang)

  In addition to constantly researching and developing new varieties, how to make seeds more suitable for modern agricultural production methods is a problem that the Corn Research Institute of Jilin Academy of Agricultural Sciences is currently thinking about.

  "At present, one of the main problems in corn production is that the level of mechanized harvesting of seeds is low. At present, the harvesting method is mechanical harvesting of ears or manual harvesting, which is not conducive to large-scale production." Zhang Zhijun, a researcher at the Corn Research Institute of Jilin Academy of Agricultural Sciences, said.

  In recent years, the corn research institute of Jilin Academy of Agricultural Sciences has taken the research and development of new varieties suitable for modern production methods as its main research goal. "At present, we have cultivated Jidan 66, Jidan 436, and Jidan 81 and 82, which will be approved soon. It can be said that grain harvesting is a strong support for Jilin agriculture to take the lead in realizing agricultural modernization in the future." Lu Ming, deputy director of the Corn Research Institute of Jilin Academy of Agricultural Sciences, said.

  Researchers overcome the difficulty of grain harvesting by machine (photo by Zhou Linhai from Yangguang. com)

  Document No.1 of Jilin Provincial Party Committee issued this year made it clear that it is necessary to implement the project of improving corn yield per unit area. Screening and popularizing new maize varieties with density tolerance, high resistance and high yield.

  "Every seed we develop must first ensure safety and good resistance. No matter what kind of environment, it can grow. The second is high yield, which allows farmers to increase their output after planting. " He Wei said. Hongxiang Seed Industry plans to reach the production capacity of all four design production lines as planned before 2025, meeting the production demand of 100,000 mu. "In the future, we can serve the whole park, let the seed industry in Jilin Province come back and build a spring corn processing base."

  It is the wish of Jilin breeders to cultivate a good seed and plant a good field, and it is also the road they will always stick to.

  Hongxiang seed industry farming field (photo by Yang Guangwang Fa Qu Liangliang)

Lansi Technology: We are actively cooperating with customers to verify the folding screen, and are ready for mass production of new models.

On April 3, Lansi Technology Co., Ltd. (Lansi Technology, 300433.SZ) said on the interactive platform of Shenzhen Stock Exchange that the company has already laid out the manufacturing technology of folding protective screens such as UTG and CPI, deeply cooperated with major brands in R&D and production, and has the ability to quickly mass-produce flexible screens and whole modules of various materials of folding screen mobile phones, and has supplied UTG and CPI screens to large domestic customers in batches. The company is the core supplier of exterior parts and structural parts for major customers in North America. Through long-term joint research and development with customers, it can ensure a high market share. At present, we are actively cooperating with customers to verify the folding screen, and the overall progress is smooth, which is ready for mass production of new models.

Investigation on the intervention of Provincial Education Department in a secondary technical school in Henan Province by forging student status and defrauding funds.

  According to Voice of China: Recently, Voice of China continued to report a secondary vocational school in Henan — — There are some problems in Henan Polytechnic School, such as forging student lists to obtain state education funds and renting state assets for illegal profits. In this regard, the staff of the Henan Provincial Department of Finance said that the school had previously had some expenses that were not uniformly registered and accounted for in the accounting books set up according to law, and that the school had been punished for privately storing public funds.

  The Henan Provincial Department of Education said that it had been investigating and verifying the forgery of the student status list to obtain education funds, but it was unable to provide reporters with the list of students used by the school to apply for per capita funding. In fact, in recent years, the problems of enrollment, charging and management of secondary vocational education are not uncommon. Then, how to supervise the chaos in secondary vocational education?

  Forged the student list, rented the teaching building, and the funds fell into the private "small treasury"

  Informed sources told reporters that in recent years, there have been many students who dropped out of school early without completing their studies, and the school information still shows that they are studying at school. Based on this, the school has obtained the education funds allocated by the province.

  Insider: "But what does it mean that students are still registered as students, and they are still registered as students?" That is, as soon as he registered, he handed it to the Education Department. This is not registered, and then this list was handed over to the Finance Department, and this student was dialed. "

  The school staff provided the reporter with a list of 118 students who dropped out of two colleges early, and the Voice of China reporter verified them one by one. All the students in this list dropped out of school for different reasons in less than one year. However, most of the students’ information shows that they are still in Henan Polytechnic School.

  Reporter: "Have you been studying in this Henan Polytechnic School for 16 years?"

  Lost students: "Yes."

  Reporter: "So you haven’t been there for a while?"

  Lost students: "About a year."

  According to the funding basis of the per-student funding of vocational schools in Henan Province, full-time vocational schools allocate funds strictly according to the number of students’ status, and the subsidies for different majors such as arts and sciences range from 5,000 yuan to 7,000 yuan per person per year. For those students who dropped out of school early, but their school status is still in school, the school theoretically received per capita funding.

  In addition, many school staff reported that the school’s income from renting state assets including the comprehensive teaching building was not recorded, and the principal set up a "small treasury" privately.

  The number of forgers and the allocation are still being verified, and the private small treasury is fined 10,000 yuan.

  In response to this matter, the Voice of China reporter contacted the Henan Provincial Department of Education many times. The relevant staff of the Department of Education responded that the relevant situation has been investigated and verified, but the Department of Education does not have a list of students provided by the school to apply for per capita funding, and the funding is the responsibility of the financial department. The reporter then contacted the Henan Provincial Department of Finance, and the staff of the Department of Finance said that the financial department allocated funds according to the data provided by the education department.

  Staff of the Finance Department: "We still record the number of students provided by the education department into our budget system, and determine its quota according to the number of students."

  In addition, the staff of the Henan Provincial Department of Finance said that an administrative penalty of 10,000 yuan had been imposed in accordance with relevant regulations.

  Expert: We should strengthen supervision and improve the funding system and methods.

  In fact, in recent years, there have been incidents of false enrollment, arbitrary charges, and taking funds from secondary vocational education. In this regard, Wang Jianzhuang, executive dean and chief researcher of Henan Institute of Private Education, said that in addition to the main responsibility of the school, the living environment of secondary vocational schools, the utilitarian consciousness of individual schools and the official standard structure of vocational schools are all factors.

  Wang Jianzhuang: "Because the competition for students is so fierce, some schools don’t run according to an educational law. Such a school, it tries to get funds through some improper means, and the per capita funding is the main source of funds for their school. Therefore, this will also have problems in system design, and this phenomenon will occur with some loopholes in supervision. "

  Wang Jianzhuang believes that to completely change this situation, we need the joint efforts of the government, schools and other parties. While improving the quality of managers in secondary vocational schools, we should improve the funding system and methods, establish a mechanism to allocate funds to the extent that graduates serve the society, encourage the growth of high-quality secondary vocational education resources, and realize scientific development.

  Wang Jianzhuang: "We use it to cultivate students’ other achievements, and its graduates serve the overall evaluation of society to allocate its funds in a planned way. For example, to evaluate a school and a secondary vocational school, there are 300 graduates this year. I will count the employment situation of your graduates through the graduates in the past five years, and I have an indicator of his contribution to the local economic and social development, and then I will give you the funds after this year in proportion, which is better. "

  Voice of China will continue to pay attention to the progress of the follow-up investigation on this matter.

  Yang Guang reporter Qian Cheng

Follow-up of a tenant’s "privately demolished load-bearing wall" in Harbin: the safety appraisal and repair scheme of the building structure passed the expert demonstration

  On June 11th, the reporter learned from the People’s Government of Songbei District in Harbin that the investigation team of "Private Demolition of Load-bearing Walls" in Limin Academy Community invited nine national authoritative experts, including China Academy of Engineering, to form an expert group to make a special demonstration on the safety appraisal and repair scheme of the building structure, and formed an expert group’s opinion that the technical work procedures such as testing, monitoring, appraisal and repair scheme preparation are reasonable, the content is comprehensive, and the analysis and appraisal results are credible.

  After the incident, Songbei District entrusted national and provincial authoritative professional institutions to comprehensively carry out related technical work such as building structure detection, deformation monitoring and structural safety appraisal, and formulated a repair plan.

  First, the National Construction Engineering Quality Inspection and Testing Center of China Academy of Building Research was entrusted to carry out comprehensive inspection on Building B of Limin Academy Community, and 248 houses were checked one by one. After verification, the total number of vertical load-bearing wall members on each floor of Unit 2, Building B of Limin Academy Community is 50, with a total cross-sectional area of 42.98 square meters. In the decoration construction, part of the wall of one component was demolished, with a cross-sectional area of about 0.48 square meters, accounting for 1.12% of the total cross-sectional area of the load-bearing wall of this floor, and the other walls were non-load-bearing walls. The test results show that 248 houses in Building B have not found any stress cracks in structural members, and all the cracks that can be seen are located in the infilled wall or the interface with the structure, which does not affect the structural safety.

  Second, the Heilongjiang Institute of Cold Building Science was entrusted to monitor the deformation of the building. The continuous monitoring for 30 days showed that the data of each monitoring point were within the allowable value of the national standard, and no abnormality was found.

  The third is to entrust Harbin Institute of Technology Engineering Testing Co., Ltd. to carry out the safety appraisal of the building structure, which shows that the whole structure is safe and stable except for the structural members adjacent to the demolition site, and it can meet the requirements of safe use after repair.

  Fourth, the architectural design and research institute of Harbin Institute of Technology was entrusted to make a restoration plan based on the appraisal report.

  Recently, an expert group composed of nine national authoritative experts, including academicians of China Academy of Engineering, national engineering survey and design masters, main compilers and examiners of national general codes, conducted a special demonstration on the safety appraisal and repair scheme of structures after illegal demolition. The expert group conducted on-site investigation and listened to the special reports from the testing unit, monitoring unit, appraisal unit, original design unit and restoration design unit. After questioning and discussion, the expert group’s opinion was formed: the temporary measures taken against the illegal removal of shear walls were timely and effective, ensuring that the structure was in a safe and controllable state at the disposal stage; The technical work procedures such as detection, monitoring, appraisal, design calculation and analysis, and preparation of repair scheme are reasonable and comprehensive, and the analysis and appraisal results are credible; It is reasonable and feasible to adopt the standard not lower than that at the time of construction to implement the restoration.

  After verification, the picture of the gables of the building passing through the big cracks in the network was previously transmitted, and the building of Building B in the non-Limin Academy Community was a network picture quoted from the media.

  It is understood that the residents of Unit 2, Building B of Limin Academy Community have been temporarily resettled, and 15 working groups have been set up in Songbei District to ensure the residents’ living services, and the first-class construction enterprises in the province will be entrusted to start the restoration construction. Songbei Branch of Harbin Public Security Bureau took criminal compulsory measures against five people, including the lessees Zhang and Ma Mouxin, the constructors Chang Moujiu and Liu Mouping, and the manager of the property company Zhang, who were suspected of negligently endangering public safety by dangerous means. Zhu Mobin, the owner of the house involved, and the property company will be severely punished according to the upper limit. The case is currently under further investigation. The Supervision Committee of the Harbin Municipal Commission for Discipline Inspection has carried out investigation on the related problems existing in this incident.

  (Headquarters reporter Wang Haijun)

Don’t sit still and wait for death in the late stage of cancer! See how celebrities succeed in fighting cancer!

Cancer is a big problem in the history of human medicine, and there is no way to completely cure it at present. In the face of cancer with extremely high mortality, life is fragile. No matter whether it is poor or rich, famous or unknown, we often see the news that celebrities have died of cancer, and we can’t help sighing, but there are also some wonderful experiences of anti-cancer success!  Many cancer patients often lose confidence in life after learning that they have cancer, do not actively treat them, or even resist treatment, and feel that treatment is unnecessary, and treatment is a waste of money. In fact, this idea is not correct. Don’t give up until the last moment. Even if cancer has not been completely overcome, after scientific and reasonable treatment with many patients, life can be continued, and even clinical cure or long-term survival with tumors can be achieved! Nowadays, there are many treatments for cancer. If it is found as early as possible and treated actively, one third of cancer can be cured. Medical "cure" is different from what people usually understand. The clinical cure here refers to the disappearance of symptoms and signs after treatment, and the tumor can not be found after image review for more than 5 years.

Today, Xiaobian, a cancer-free home, will share the stories of four celebrities who have succeeded in fighting cancer, and see how they fight cancer. I hope to give some reference and motivation to all cancer friends!

Kai-Fu Lee: From the late stage of cancer to the disappearance of tumor, chemotherapy+targeted therapy against advanced lymphoma.

  On September 5th, 2013, 52-year-old Kai-fu Lee, the founder of Innovation Factory, announced that he had stage IV follicular lymphoma and had to leave work for treatment. In February 2015, he announced the results of his physical examination, indicating that the tumor in the body is not obvious at present. In June of the same year, Kai-fu Lee said that he had not found any lesions in his last two examinations and ridiculed himself as "Li Kangfu". It took Kai-fu Lee less than two years from finding out the cancer until the focus was completely gone. His anti-cancer experience is worth learning from.  

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Lymphoma, also known as lymphoma, occurs in the lymphatic system and is one of the malignant diseases of the blood system. In fact, we are no strangers. Besides Kai-Fu Lee, celebrities such as Luo Jing, Asan and Cindy Lee have also suffered from lymphoma. The incidence of lymphoma is actually not too high in malignant tumors, which is about 5/100,000. It can occur at any age, but it is mainly in middle-aged people aged 30-50. The malignant degree of different types of lymphoma varies greatly, which can be roughly divided into: inertia, aggression and high aggression. Inertial lymphoma is similar to chronic diseases, while high aggression is like a "death warrant"! There are many types of lymphoma, but as long as we know, lymphoma can be divided into Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL), the latter accounting for about 90%, and diffuse large B-cell lymphoma is the main type (40%~50%). When you know that you have stage 4 or systemic metastasis, it doesn’t mean that your condition is very serious and there is no cure. Don’t give up treatment easily. The treatment of lymphoma is mainly systemic chemotherapy and radiotherapy. Li Kaifu’s treatment plan is that bendamustine (bendamustine) is combined with rituximab (rituximab, trade name: rituximab). Different from traditional chemotherapy drugs, rituximab is called "an artifact to accurately combat lymphoma". It is an anti-CD20 monoclonal antibody against malignant B lymphocytes, with good effect and little side effects, and it is a milestone in the treatment of lymphoma.  

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Since rituximab was listed in the United States in 1999, the 5-year survival rate of patients with diffuse large B-cell lymphoma has increased to 50%. Rituximab used to be a self-funded drug, which was expensive. Now it has been included in the scope of medical insurance reimbursement, which has enabled many cancer friends to enjoy the fruits of modern medical progress.  

In addition, Kai-Fu Lee also tried many kinds.Natural therapyIn order to finally defeat cancer.

Keeping a good sleep is the most important thing. Staying up late for a long time may reduce the body’s immunity, and his lymphoma is a common cancer in the immune system. Therefore, after suffering from cancer, he made a schedule to protect his immunity. It is necessary to keep your mouth shut when disaster comes from your mouth. It is particularly important for cancer patients to keep their mouths shut, and maintaining good eating habits can better fight cancer. Kai-fu Lee suggested that everyone should eat more grains, beans, fruits and vegetables, and take a balanced intake. 3. Take your legs apart and exercise properly to inhibit cancer cells. Many studies have confirmed that exercise is beneficial to the rehabilitation of cancer patients and can reduce the risk of cancer recurrence after operation. However, it should be reminded that not all exercise is suitable for cancer patients, and it is suggested to use the principle of "not feeling tired". 4. Good attitude, get twice the result with half the effort When fighting cancer, it is very important to keep a good attitude, which has a great influence on cancer treatment.

Pancreatic cancer: steinman "tried medicine by himself", and the dendritic cell vaccine made him live for four and a half years!

  Speaking of vaccines, everyone is actually familiar with them, except for the common hepatitis B vaccine and influenza vaccine, and the Covid-19 vaccine that we have vaccinated up to now. In fact, cancer vaccine is also a form of immunotherapy, which can prevent cancer from developing or kill existing tumors by stimulating or restoring the human immune system. In the 21st century, the high incidence of cancer has attracted the attention of the global medical community. As a prominent tumor vaccine, dendritic cell vaccine has been a research hotspot in this field. When it comes to dendritic cell vaccine, we have to mention a legendary figure-ralph steinman, winner of the 2011 Nobel Prize in Physiology or Medicine. 2851633735018673   

ralph marvin steinman After the diagnosis of pancreatic cancer in 2007, steinman actively tried a therapeutic vaccine (DC vaccine) based on dendritic cells. With the help of this "cellular immunotherapy", his life was extended from the expected months to four and a half years.  There is a rule in the Nobel Prize that they never give this prize to people who have passed away. However, ralph steinman broke this rule because he passed away quietly three days before receiving the call for winning the prize. Therefore, Staman is also called the most regrettable Nobel Prize winner.

  0one  Suffering from pancreatic cancer with a mortality rate of 95%, he devoted himself to the research of DC vaccine.

In 1973, steinman discovered dendritic cells in the spleen of mice, and put forward the concept of dendritic cells. In 2011, steinman shared the Nobel Prize in Physiology or Medicine with Jules Hoffman and Bruce Beutler for "discovering dendritic cells and their role in the acquired immune system".

Pancreatic cancer, which claimed steinman’s life, is one of the malignant tumors with the highest mortality rate at present. The mortality rate of this disease can reach 95% clinically, and it is very rare for patients who can survive for 5 years after being diagnosed with this disease (< 5%). There is no approved cancer vaccine for pancreatic cancer, and the prognosis is very poor. The survival time of advanced patients is weeks or months. The disease is usually treated with the cytotoxic drug gemcitabine. However, this treatment seems to be mainly used for palliative treatment of advanced pancreatic cancer, which can improve the quality of life and prolong the median survival time of 5 weeks. Most patients will soon develop resistance to this drug. Therefore, the indomitable Professor steinman tried to use dendritic cell vaccine to treat his pancreatic cancer. Dendritic cells are the main antigen presenting cells (APC) in the immune system. They process antigenic substances (for example, from invading bacteria and viruses, and from cancer cells) and present antigens on their surfaces to other types of immune cells, especially T cells. This leads to antigen-specific activation of T cells. Therefore, dendritic cells act as the main link between innate immune system and adaptive immune system. 

02  After eight treatments, dendritic cell vaccine made him live for four and a half years!

  Professor steinman tried eight experimental therapies, one at a time. For each of these treatments, he and his colleagues submitted a single-patient use agreement to the FDA and obtained the approval of the agency. In these treatments, there are three kinds of cancer vaccines, and steinman finally used the dendritic cell vaccine from his own tumor instead of the cell line. Patients with advanced pancreatic cancer usually have poor prognosis. The median survival time of locally advanced and metastatic pancreatic cancer (advanced pancreatic cancer accounts for more than 80% of individuals diagnosed with the disease) is about 10 months and 6 months respectively. For all stages of pancreatic cancer, the 1-year and 5-year relative survival rates were 25% and 6%, respectively. However, Dr. steinman’s life span has been extended from several months to four and a half years! Since then, the medical community has launched a craze for the research and development of dendritic cell vaccines, which has become a kind of immunotherapy with more research and development achievements in recent years. At present, the dendritic cell vaccines approved by the FDA and many clinical trials entering the third phase are worth looking forward to. Since 2010, exceptThe FDA approved the first dendritic cell vaccine Provenge(sipuleucel-T) for the treatment of refractory prostate cancer. Dendritic cell vaccine has achieved good results in all kinds of cancer. Such as brain tumor-DC VAX-L vaccine, melanoma-—TLPLDC vaccine, renal cancer-—ilixadencel vaccine, newly diagnosed glioblastoma-AV-GBM-1 vaccine, lung cancer-CCL 21-dendritic vaccine, breast cancer -Her2 pulsed dendritic cell vaccine, etc.Xiaobian will not go into details here.

Nasopharyngeal Carcinoma: After 33 proton treatments, Li Zongwei successfully returned to badminton.

  As the uncrowned king of badminton in the world, Li Zongwei, a famous Malaysian badminton player, has a brilliant career, with three runners-up in the Olympic Games, four runners-up in the World Championships, one runner-up in the soup cup and one silver medal in the men’s singles in the Asian Games. However, on July 25, 2018, he met another more powerful opponent-nasopharyngeal cancer. According to Malaysian media reports, Li Zongwei suddenly announced his withdrawal from the World Badminton Championships and the Asian Games badminton competition, and was later confirmed to have early nasopharyngeal carcinoma in September. However, Li Zongwei was not defeated by the disease. After 33 proton treatments of 25 minutes each time for more than two months, the doctor said that all the cancer cells in his body had been eliminated. In October of the same year, after he announced the success of anti-cancer, he said that he would return to badminton in December. Perhaps Li Zongwei is not a "winner" in badminton. Although he has won numerous titles, he has never won a world championship, including a slightly dismal record against Lin Dan. This time, however, in the face of this "competition" with the same disease, he finally won. This win will be the greatest capital of his life. In terms of treatment, it is difficult to perform radical surgery because of the special location and unclear boundary of nasopharyngeal carcinoma, the deep and narrow nasopharyngeal cavity, and many important blood vessels, cranial nerves and lymphoid tissues around it. But nasopharyngeal carcinoma is sensitive to radiotherapy, Therefore, radiotherapy is the main treatment for nasopharyngeal carcinoma, especially proton therapy. As the "king" of "precision radiotherapy", it can not only show its talents, but also effectively prevent the side effects of radiotherapy.

Proton therapy is a "qualitative leap" in tumor radiation!

  Proton therapy is to accelerate the nucleus of hydrogen atom (i.e. proton) which has lost electrons to about 70% of the speed of light by using cyclotron or synchrotron. After being accelerated by the accelerator, protons with positive charges become very penetrating ionizing radiation, which enters the human body at a very high speed, is guided by special-shaped equipment, and finally reaches the targeted tumor site. Because of its high speed, the chance of interaction with normal tissues or cells in the body is extremely low. When it reaches a specific part of the tumor, the speed suddenly decreases and stops, and the maximum energy is released, resulting in a "Bragg peak", which can kill cancer cells without causing damage to surrounding tissues and organs.

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When tumors are directly adjacent to important organs or structures, such as spinal cord, optic nerve and heart, proton therapy can still effectively treat tumors while protecting the functions of these important organs or structures, which is impossible in conventional radiation therapy.

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The high radiation dose is concentrated in the tumor site, and there is no/little dose in the surrounding normal tissues.

    

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Legend: The radiation of Intensity Modulated Proton Therapy (IMPT) is mainly concentrated around the focus of nasopharyngeal carcinoma, with little or no influence on the surrounding normal tissues, while the radiation area of Intensity Modulated Radiotherapy (IMRT) is large, covering the focus and surrounding normal tissues.

Melanoma: "cured" after 4 months, immunotherapy made Carter the "longest-lived president"

  In August 2015, former US President Carter was diagnosed with malignant melanoma, and liver metastasis and brain metastasis have occurred, so he is an out-and-out terminal patient. But just four months later, at an event in December, 91-year-old Carter announced that he had just confirmed after a general examination that the lesions in his body had disappeared.  

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It is understood that Carter used comprehensive therapy. First, the visible tumor was surgically removed, then the intracranial tumor was treated by radiotherapy, and finally the PD-1 drug Keytruda of Merck was used. After the brain cancer cells disappeared, Carter said that he would continue to use Keytruda for treatment. This incident made immunotherapy popular all over the world overnight. PD-1/PD-L1 and CTLA-4 pathways are crucial to the immune system’s ability to control cancer growth. These pathways are often called immune checkpoints. Many cancers will use these ways to escape the immune system. Specific antibodies to immune checkpoint inhibitors can block these pathways to deal with cancer. Once the immune system can find and deal with cancer, it can stop or slow down the development of cancer. Having said that, I have to mention the biggest difference between immunotherapy and traditional treatment, that is The trailing effect of immunotherapy, that is, patients who benefit from immunotherapy can continuously obtain stable results and bring long-term survival.

This article is original for a cancer-free home, and it needs authorization to reprint.

Behind the dystocia of intellectual S7, where is the future of HarmonyOS Zhixing?

  Huawei-related topics are always one of the hot spots in the industry.

  Recently, a chat record involving the dystocia of the first model of the Zhijie brand, which Chery cooperated with Huawei, quickly circulated on the Internet and continued to ferment. In the chat record, a netizen suspected of being a Chery employee directly pointed the finger at Huawei for the dystocia of Zhijie S7, and revealed that "the leader who has been working hard to promote cooperation with Huawei directly resigned."

  Subsequently, the leader was confirmed as Han Biwen, deputy general manager of Chery Automobile Co., Ltd. and general manager of the manufacturing division. However, on January 31, the reason for Wang Chuan’s departure was denied by Chery’s spokesperson Jin Yibo: the cooperation between the two parties was smooth, and they were making every effort to promote the production and delivery of Zhijie S7, and they had invested more resources and would continue to deepen cooperation.

  But this response does not seem to be recognized by the public.

  The intellectual S7 is "far ahead" and "far away"

  After questioning, M7 went against the trend and returned to the mainstream market after its listing, which made its new cooperation project Zhijie Automobile become the focus of public attention. However, in 2024, the delivery of the new M7 four-wheel drive version, the delayed delivery of Aouita 12 and the dystocia of Zhijie S7 made Huawei’s new models collectively face the delivery problem.

  For the first two, whether it is CMO Li Pengcheng, vice president and chief marketing officer of Aouita Science and Technology, or all the suppliers visited by Gaspar, it is attributed to the fact that the sales of products far exceeded expectations, resulting in insufficient supply. "At present, the production capacity is climbing, and the supply shortage will be alleviated as soon as possible in the past two weeks." A practitioner who supplies the new M7 precursor parts in the world revealed to Gaspar.

  However, compared with the sweet burden of the new M7 and Aouita 12, the intellectual S7 is still shrouded in gloom.

  On January 15th, Zhijie Automobile issued a document on its official account, saying that the factory is making every effort to produce and ensure high-quality delivery. This subsidy is mainly for users who have made a decision between November 28th, 2023 and January 15th, 2024. They can enjoy the subsidy after waiting for more than 6 weeks, and they can get a maximum subsidy of 10,000 yuan in 200 yuan every day.

  Previously, there had been a lot of rumors on related forums and social platforms that Zhijie S7 was delayed in delivery and not delivered in order. Just one week after the release of the above compensation plan, Gaspar learned from the relevant sales staff that the official promised delivery time has been extended from 6 weeks to 10-12 weeks.

  On November 28th, 2023, Huawei released the first pure electric car-Zhijie S7 under the smart car selection business model, which is the first product of Zhijie brand and the first model of cooperation between Huawei and Chery under the smart car selection business model.

  According to the latest news, as of the end of December, the large quantity of Zhijie S7 has exceeded 10,000, and the number of offline stores has exceeded 100 in a single day. However, according to the terminal data of Geshi Automobile Research Institute, in December 2023, the cumulative sales volume of Zhijie S7 nationwide was only 305, and according to the staff of Zhijie Automobile’s delivery center in Shanghai, there was only one centralized delivery in December last year, and there were no new cars afterwards.

  Obviously, it seems difficult to copy and paste it on Zhijie S7 due to excessive sales and insufficient production capacity. You know, compared with the manufacturing strength of Cyrus, the new "Intelligent Networked Super Factory No.2" built by Chery has a planned annual production capacity of 500,000 vehicles, which makes it hard to believe that Zhijie S7 will be difficult to produce.

  In this regard, the senior analyst of Gaspar Automotive Research Institute believes that instead of the high centralization of Huawei in software, it is more inclined to the imbalance of production rhythm between the two parties after the release of new cars, the yield of supply chain parts in mass production of new technologies and the insufficient preparation of the production line of the automobile factory are all reasons for the delay in mass production of Zhijie S7.

  The rumor that "Huawei has no basic respect for Chery" may not be groundless. Some insiders pointed out to Geshi Automobile that in the car-making business, Huawei really wants to dominate the whole process of new cars, but in cooperation with enterprises with scale advantages such as Chery and Changan, they also don’t want to be only supporting roles, and conflicts in product dominance and management styles and cultures of different companies are inevitable.

  The success of asking the world may be difficult to replicate.

  As we all know, with more than 30 years of profound accumulation in the ICT field, Huawei has cut into the car track in three modes: standardized parts suppliers, HI mode and HarmonyOS Zhixing, and the cooperation has gone from shallow to deep.

  Among them, HI mode is provided by Huawei with full-stack smart car solutions such as intelligent cockpit, intelligent driving and intelligent Che Yun, such as the cooperation of BAIC Extreme Fox and Aouita brand; In addition to providing parts and solutions, HarmonyOS Zhixing will also fully participate in product design, brand building, sales channels and other aspects, such as the cooperation with Cyrus, and so on.

  According to Yu Chengdong’s plan, Huawei’s automobile business unit (Car BU) plans to make a profit in 2025, so as to change the situation that "Car BU is Huawei’s only loss-making business". To achieve this goal, it is necessary to ensure that the cumulative sales volume of HarmonyOS Zhixing and HI mode reaches 1 million vehicles.

  It is worth noting that according to the terminal data of Geshi Automobile Research Institute, in 2023, the cumulative sales volume including Aouita 11/12, Wenjie M5/M7/M9 and Zhijie S7 was only 114,000.

  This means that Huawei BU must accelerate the pace of implementation this year. On January 16th, the day after HarmonyOS Zhixing implemented the compensation scheme of Zhijie S7, a wholly-owned new company, Huawei Car BU, was formally established. On the same day, the joint venture between Huawei and Changan also made new progress. Changan Automobile revealed that the new joint venture between Changan and Huawei was tentatively named "Newcool".

  As for Yu Chengdong, Huawei will also cooperate with BAIC and JAC respectively in HarmonyOS Zhixing business after consulting with the intellectual community. The brand of cooperation between Huawei and BAIC HarmonyOS Zhixing mode is determined as "enjoying the world", and the first model is positioned as a medium and large car, which will be officially released before the Beijing Auto Show in April; The brand of HarmonyOS Zhixing, which cooperates with Jianghuai, is designated as "Aojie", and the first car will be released in Q4, 2024, which is a million-level product.

  According to the latest news, as of January 28th, the cumulative sales volume of vehicles in the car industry in January has exceeded 28,000, setting a new record for the highest monthly sales volume. According to the data on January 9th, the cumulative delivery volume of the new M7 has reached 48,552 vehicles, and the cumulative sales volume has exceeded 120,000 vehicles. It is worth mentioning that, in addition to the new M7, the two models of the AITO series, the M5 and M9, have also received much attention. With the launch of mass delivery of the M9 and the launch of the new SUV model M8, it is expected to further promote the sales of the M 9 brand to a new high.

  Therefore, to a certain extent, S7, the first model of Zhijie brand, has become the key to whether Huawei’s HarmonyOS Zhixing model can win the cooperation between car companies.

  However, in the view of senior analysts of Gaspar Automotive Research Institute, the core sales source of HarmonyOS Zhixing model in the future will still be the contribution of the products that have cooperated with Cyrus, and it is also Huawei’s most "obedient" and recognized partner in this model, and the products of other enterprises may not have much sales performance. "The delay in the delivery of the intelligent S7 will inevitably affect the user’s car purchase choice, which in turn will affect the confidence of cooperation between the two parties."

  Zhu Huarong, the chairman of Changan Automobile, who established a new joint venture with Huawei, is even more outspoken in his resistance to HarmonyOS Zhixing. He stressed that Changan must have its own brand and choose Hi mode because it conforms to the national industrial policy. The implication is that under the HarmonyOS Zhixing model, the division of labor between Huawei and car companies is unclear, which may lead to problems in the protection of rights and interests in the process of users using cars.

  There is a clearer positioning, which is the insistence of Changan Automobile, and I believe it is not just the insistence of Changan Automobile.

  In tHis context, the above analysts believe that hi mode will still have enterprises to adopt cooperation, especially domestic car companies, mainly to complement their intelligent shortcomings and learn from the organization and management of Huawei IPD. In addition, Huawei Car BU Yinwang Technology Co., Ltd. has a very large room for growth in the future by binding car companies to create an "ASML model" in the smart car ecosystem.

  As mentioned earlier, Huawei’s circle of friends continues to expand rapidly. If all goes well, it is not out of reach to achieve the goal of one million vehicles in 2025. However, the success of the world of inquiry has not made all brands resolutely hand over the dominant position like Cyrus, and the constant disputes in the intellectual world have made Huawei’s future in the last three "circles" full of uncertainty. How to balance the needs and cooperation of different car companies may become a more critical focus of Huawei HarmonyOS Zhixing in the future than expansion. (Garcia)

Shi Feida starred in the new short play "Clouds Going Up", which is about to go online to interpret the guardian in the Gu Wu world.

Produced jointly by Wenhuaren (Beijing) Culture Media Co., Ltd. and Fengxing Online, the highly anticipated short play "Clouds Going Up" will be officially launched on May 10th. With its unique world outlook of coexistence of ancient martial arts civilization and modern civilization, the play has attracted a large number of audiences’ attention. In this work, Shi Fei Da, a powerful actor, will play Wen Yu, the eldest brother of the three brothers and sisters of the Wen family, which has attracted strong attention from fans.

Shi Feida, who is 178cm tall and weighs 65kg, has a handsome appearance and unique temperament. He is a versatile actor with rich acting experience. As early as 2010, he partnered with Ni Ping, a famous actor and host, to host the Third China Artists Awards Ceremony in world artists association, USA, and won the Best Newcomer Award. This honor not only affirmed his hosting talent, but also predicted his infinite possibilities in the future.

While at school, he was lucky enough to participate in the film Far away Xilin Gol directed by the famous director Gao Feng, and he played Guo Qinglin (first hero), an educated youth in Beijing, and accumulated valuable performance experience. After graduation, he devoted himself to the shooting of many main melody films, constantly challenging himself and improving his acting skills.

In the anti-Japanese war film Sun Face directed by Xinyun Zhu in 2013, Shi Feida played Zhou Maosong, and his superb acting skills and solid lines were widely recognized in the industry. Whether it is the emotional expression of the role or the interpretation of the action play, he has shown excellent professionalism and acting talent.

In addition, Shi Feida’s performance in the film field is also quite eye-catching. His film works include Strange Crime, Qian Xuesen, Far-off Xilin Gol, Lost, Music and Whose Child. In these works, he created many characters with different personalities and distinct images, which showed his diversity and plasticity as an actor.

In the upcoming short play "Clouds Going Up", Shi Fei Da will play Wen Yu, the eldest brother of Wen Ji’s family, which is a role full of sense of justice and responsibility. In Yun Kaminooji, a world where ancient martial arts civilization and modern civilization coexist, he will lead his younger brothers and sisters to protect ancient martial arts civilization, maintain modern order and present a legendary heroic image for the audience.

Shi Feida said that he was very excited and looking forward to playing such a role. He believes that the story background and role setting of "Up in the Clouds" are very attractive, and he will devote himself to shaping the role and bring a brand-new and unforgettable performance to the audience. With the upcoming launch of Clouds Going Up, the audience are full of expectations for Shi Feida’s performance in the play. I believe that he will bring a double feast of vision and mind with superb acting skills and profound performance skills.

"Clouds Going Up" is not only a wonderful short play that combines ancient martial arts civilization and modern civilization, but also a masterpiece that shows the brilliance of human nature and heroic feelings. With the participation of many outstanding actors such as Shi Fei Da, the play will surely become the focus of the audience’s attention. Let’s look forward to the arrival of May 10th and witness the wonderful performance of Shi Feida in Clouds Up.

Scientists found that the smallest reptile on the earth is only 22 mm long.

  German scientists have discovered a magical chameleon subspecies in northern Madagascar. They are only the size of melon seeds and can lie on human fingers, which may be the smallest reptile on the earth.

  The Bavarian National Zoo in Munich, Germany, said that they found two adult miniature chameleons, a female and a male, in northern Madagascar. Among them, the male is only 22 mm long, which is the smallest known reptile. The other female chameleon is a little bigger, but the total length is only 29 mm.

  The researchers said that it is not clear why the species is so small, but perhaps similar to the "island effect", animals trapped on the island and with small habitats tend to evolve smaller bodies.

  However, the living environment of this new species is worrying. The habitat of this chameleon has been destroyed by deforestation. Fortunately, in recent years, the government has planned a protected area in the local area, so they are lucky to survive.

No Blowing, No Black: What about the plug-in hybrid of Volvo XC60? There is still a lot of room.

When our career is stable and our income is gradually "well-off", our originally poor life has also changed a lot, and the car we once yearned for is no longer out of reach. The late car cost of plug-in hybrid is the point that its potential consumers pay more attention to. Let’s look down with Xiaobian.

Let’s take a look at the appearance of the Volvo XC60 plug-in hybrid. The Volvo XC60 plug-in hybrid front is avant-garde and looks more delicate. Headlights are very avant-garde, and the overall look has a certain sense of hierarchy. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, automatic steering, delayed closing and so on. Coming to the side of the car body, the size of the car body is 4708 mm * 1902 mm * 1656 mm. The car adopts sharp lines, and the side gives a very tough feeling. With large-sized thick-walled tires, smooth lines run through the whole side of the car. In the design of the rear end, the rear end looks more capable, and the taillights give people a very sharp feeling, and the shape is relatively hard.

Sitting in the car, the Volvo XC60 plug-in hybrid interior looks very comfortable, and the overall visual effect is very distinctive. The steering wheel of the car is very cute, made of leather, and the shape is very fighting. Take a look at the central control, with a 9-inch touch-sensitive LCD central control screen, which makes the interior style impressive and gives people a sense of simplicity and generosity. Finally, let’s take a look at the dashboard and seats. The car is equipped with a stylish dashboard with a sense of technology. The car adopts leather seats, and is equipped with functions such as electric adjustment with memory in the auxiliary seat, electric adjustment with memory in the seat, and seat proportion tilting, which further improves the comfort of the driver and passenger.

Next, look at the configuration. Volvo XC60 plug-in hybrid is equipped with car networking, driving mode selection, remote control key, rear wiper, traction control (ASR/TCS, etc.) and other configurations.

The moderate size of the car is a very suitable choice for many families, and the internal space is enough for daily use in families. As long as you really like it, it’s over. Go to the 4S shop and place an order.